Avaliação da atividade fotoprotetora de Achillea millefolium L. (Asteraceae)

Souza, Thana Mara de; Santos, Luis Eduardo dos; Moreira, Raquel Regina Duarte; Rangel, Vera Lucia Borges Isaac

doi:10.1590/s0102-695x2005000100008

Cited by 27 publications

(27 citation statements)

References 3 publications

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“…The SPF results obtained in our experimental study are consistent with findings reports in previous studies (Silva et al, 2005;Souza et al, 2005;Lopes et al, 2007;Violante et al, 2009;Ferrari, Rocha-Filho, 2011;Mansur et al, 2012). The cited studies described the difficulty in increase in the SPF value by the addition of natural active agents in the formulation containing chemical and/or physical UV filters.…”

Section: Sun Protection Factor Study (Spf)supporting

confidence: 93%

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Development of O/W emulsions containing Euterpe oleracea extract and evaluation of photoprotective efficacy

Daher

Fontes

Rodrigues

et al. 2014

Braz. J. Pharm. Sci.

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Euterpe oleracea Mart. is a palm tree popularly known as açai, which is primarily found in northern Brazil. The açai's fruits contain anthocyanins, a class of polyphenols to which antioxidant properties have been attributed. The aim of this work was to develop O/W sunscreens emulsions containing açai glycolic extract (AGE) and to evaluate both their physical stability and photoprotective efficacy. Emulsions containing AGE and sunscreens were formulated using different types and concentrations of polymeric surfactant (acrylates/C 10-30 alkyl acrylate crosspolymer and sodium polyacrylate). The influence of two rheology modifiers (polyacrylamide (and) C13-14/isoparaffin (and) Laureth-7 and Carbomer) on the stability was also investigated. Physical stability was evaluated by preliminary and accelerated studies. Emulsions with 1.0% sodium polyacrylate were stable and exhibited non-newtonian pseudoplastic behavior and thixotropy. Photoprotective efficacy was evaluated by in vivo Sun Protection Factor (SPF) and determination of Protection Factor of UVA (PF-UVA). When AGE was added to the sunscreen emulsion, no significant increase in the in vivo SPF value was observed. The emulsion containing AGE showed PF-UVA = 14.97, 1.69 of the SPF/PF-UVA ratio and a critical wavelength value of 378 nm, and may therefore be considered a sunscreen with UVA and UVB protection. Euterpe oleracea Mart. é uma palmeira popularmente conhecida como açaí, encontrada no norte do Brasil. O fruto do açaí apresenta em sua composição antocianinas, uma classe de polifenóis à qual é atribuída propriedade antioxidante. Os objetivos desse trabalho foram desenvolver emulsões fotoprotetoras O/A contendo extrato glicólico de açaí (AGE), avaliar a estabilidade física e avaliar a eficácia fotoprotetora. Emulsões contendo AGE e filtros solares foram formuladas utilizando diferentes tipos e concentrações de tensoativo polimérico (acrilates/C 10-30 alquil acrilato polímero cruzado e polilacrilato sódico). A influência de dois modificadores reológicos (poliacrilamida (e) C13-14/isoparafina (e) Laureth-7 e Carbomer) na estabilidade foi avaliada. A estabilidade física das emulsões foi avaliada por meio de estudos de estabilidade preliminar e acelerada. Emulsões com 1,0% poliacrilato sódico foram estáveis, exibiram comportamento não-newtoniano pseudoplástico e tixotrópico. A eficácia fotoprotetora foi avaliada pelo teste in vivo de Fator de Proteção Solar (FPS) e pela determinação do Fator de Proteção UVA (FP-UVA). Quando adicionado o AGE na emulsão contendo filtros solares, não se observou aumento significativo no valor do FPS. A emulsão contendo o AGE apresentou FP-UVA=14,97, a razão FPS/ FP-UVA = 1,69 e o comprimento de onda crítico igual a 378 nm, podendo ser considerado um protetor solar com proteção UVA e UVB. Unitermos:Emulsão O/A/desenvolvimento. Euterpe oleracea/farmacognosia. Euterpe oleracea/extrato glicólico/eficácia fotoprotetora. Protetores Solares/desenvolvimento. Fator de Proteção Solar.

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Section: Sun Protection Factor Study (Spf)supporting

confidence: 93%

“…Vegetal extracts containing flavonoids (e.g., Achillea millefolium, Hamamelis virginiana, Matricaria chamomilla, Mentha piperita and Salvia officinalis), reported in previous studies, were shown to be capable of absorbing ultraviolet radiation (Bobin, Raymond, Martini, 1994;Souza et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Development of O/W emulsions containing Euterpe oleracea extract and evaluation of photoprotective efficacy

Daher

Fontes

Rodrigues

et al. 2014

Braz. J. Pharm. Sci.

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“…In general, the UV-Vis absorption spectrum of flavonoids shows two peaks of maximum absorption (240-280 nm and 300-550 nm), similar to what was presented by B. laciniosa extracts [25]. Therefore, the flavonoids content produced by plants is considered an important protection factor against UV radiation [26].…”

Section: Resultsmentioning

confidence: 93%

Phytochemical analysis and evaluation of antioxidant and photoprotective activities of extracts from flowers ofBromelia laciniosa(Bromeliaceae)

Oliveira-Júnior

Ferraz

Souza

et al. 2017

Biotechnology & Biotechnological Equipment

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In this study, the phytochemical profile of extracts from the flowers of Bromelia laciniosa was characterized. The total phenolic and flavonoids contents were determined and the antioxidant and photoprotective activities were evaluated using in vitro assays. Phytochemical analysis demonstrated that the extracts were found to be positive for the presence of anthracene derivatives, anthraquinones, coumarins, flavonoids and tannins, lignans, mono and diterpenes. The ethanol extract (Bl-EtOH) presented the most significant total phenolic content (53.75 § 1.25 mg GAE/g). The dichloromethane extract (Bl-CH 2 Cl 2 ) showed the highest flavonoid content (46.06 § 1.18 mg CE/g). The methanol extract (Bl-MeOH) was the most effective extract in the DPPH (2,2-diphenyl-1-picrylhydrazil) assay (EC 50 141.90 § 3.01 mg/mL). Bl-EtOH and Bl-MeOH showed higher sun protection factor at a concentration of 100 mg/L (3.38 § 0.04 and 3.78 § 0.11, respectively). Therefore, the extracts proved to be interesting for the development of new studies aiming their incorporation into photoprotective cosmetic formulations.

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“…Diversos trabalhos demonstraram que as plantas que absorvem na região ultravioleta Avaliação in vitro da atividade fotoprotetora de extratos vegetais do cerrado de Mato Grosso apresentam em sua composição complexa, diferentes moléculas, destacando-se metabólitos especiais como os flavonóides, taninos, antraquinonas, alcalóides e os polifenóis (Bobin et al, 1994;Henriques et al, 2000;Falkenberg et al, 2000;Zuanazi, 2000;Goossens & Lepoittevin, 2003;Souza et al, 2005;Di Mambro & Fonseca 2006).…”

Section: Resultsunclassified

“…Souza et al (2005) estudaram os extratos das flores e folhas da Achillea millefolium, planta que apresenta flavonóides em sua composição, mas não foram efetivos para o preparo de um produto fotoprotetor.…”

Section: Resultsunclassified

Avaliação in vitro da atividade fotoprotetora de extratos vegetais do cerrado de Mato Grosso

Violante¹,

Souza²,

Venturini³

et al. 2009

Rev. bras. farmacogn.

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RESUMO:O cerrado brasileiro é um bioma detentor de grande diversidade biológica. No entanto, são escassas as pesquisas de espécies vegetais, especialmente do cerrado mato-grossense, com potencial para serem utilizadas como filtros solares naturais. O objetivo desta pesquisa foi estudar o potencial fotoprotetor de espécies de diferentes famílias (Apocynaceae, Lythraceae, Oxalidaceae) do cerrado da região do Rio Manso, Chapada dos Guimarães -MT. A absorbância dos extratos etanólicos secos foram medidas em diferentes concentrações entre os comprimentos de onda de 260 a 400nm para verificar a absorção nas regiões ultravioleta A e B (UVA e UVB). As plantas que apresentaram absorbância na região estudada foram submetidas a uma análise fitoquímica qualitativa preliminar para determinar a presença de polifenóis e alcalóides, constituintes característicos de plantas que absorvem a radiação UV. Os extratos etanólicos secos que apresentaram absorção em UVB foram submetidos ao teste de determinação in vitro do Fator de Proteção Solar (FPS) desenvolvido por Mansur. M. Velame apresentou absorção na região UVB com absorbância máxima em 318nm, enquanto que a L. pacari e O. hirsutissima apresentaram absorbância na região UVA. Na concentração utilizada e padronizada, nenhuma das espécies apresentou FPS ≥2, sendo assim não podem ser consideradas plantas com potencial fotoprotetor.Unitermos: Apocynaceae, atividade fotoprotetora, Cerrado de Mato Grosso, fator de proteção solar in vitro, Lythraceae, Oxalidaceae.ABSTRACT: "In vitro sunscreen activity evaluation of plants extracts from Mato Grosso cerrado". The Brazilian savanna is a holding biome of large biological diversity. However, the researches of plants species are scarce, especially at the Mato Grosso´s savanna; which have potential to be used as natural sunscreen. The objective of this research was to study the photoprotector potential of several species (Apocynaceae, Lythraceae, Oxalidaceae) from the savanna´s region at the Manso River, Chapada dos Guimarães -MT. The absorbance of dry ethanolic extracts were measured in different concentrations, between waves from 260nm until 400 nm in length. Just to check the absorption in the A and B ultraviolet regions (UVA and UVB). The plants that presented absorbance by the studied area were submitted to a preliminary qualitative phytochemical analysis to determine if there are polyphenols and alkaloids inside, because they are typical constituents of plants that absorber the UV radiation. The dry ethanolic extracts, that presented absorption in UVB, were submitted to a in vitro Sun Protection Factor (SPF) determination test, developed by Mansur. M.velame presented absorption in the UVB region with maximal absorbance at 318 nm, while L. pacari and O. hirsutissima presented absorbance in the UVA region. At the used and standardized concentration, no species presented SPF ≥ 2, so they cannot be considered plants with photoprotector potential.

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Avaliação da atividade fotoprotetora de Achillea millefolium L. (Asteraceae)

Cited by 27 publications

References 3 publications

Development of O/W emulsions containing Euterpe oleracea extract and evaluation of photoprotective efficacy

Development of O/W emulsions containing Euterpe oleracea extract and evaluation of photoprotective efficacy

Phytochemical analysis and evaluation of antioxidant and photoprotective activities of extracts from flowers ofBromelia laciniosa(Bromeliaceae)

Avaliação in vitro da atividade fotoprotetora de extratos vegetais do cerrado de Mato Grosso

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