Autotransplantation of Frozen Testicular Tissue in Monorchid Rats Treated With Cisplatin

Baltogiannis, D.; Pardalidis, N.; Giannakis, Dimitrios; Tsabalas, S.; Giotitsas, N.; Tsounapi, P.; Watanabe, Tetsuo; Miyagawa, Ikuo; Sofikitis, N.

doi:10.1016/s1569-9056(08)60083-4

Cited by 1 publication

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“…Grafting of testis tissue was developed as a tool for androgen substitution in the 1950s [124] and, consequently applied to study steroidogenesis and Sertoli or Leydig cell functions [125]. Historically, autografting of frozen testicular tissue in monorchid rats was performed to understand testicular tissue function [126]. Till date, autografting of cryopreserved testicular tissues is reported only in rhesus monkey.…”

Section: Autografting Of Gonadal Tissuesmentioning

confidence: 99%

Fertility preservation through gonadal cryopreservation

Devi

Goel

2016

Reprod Medicine & Biology

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Fertility preservation is an area of immense interest in today's society. The most effective and established means of fertility preservation is cryopreservation of gametes (sperm and oocytes) and embryos. Gonadal cryopreservation is yet another means for fertility preservation, especially if the gonadal function is threatened by premature menopause, gonadotoxic cancer treatment, surgical castration, or diseases. It can also aid in the preservation of germplasm of animals that die before attaining sexual maturity. This is especially of significance for valuable, rare, and endangered animals whose population is affected by high neonatal/juvenile mortality because of diseases, poor management practices, or inbreeding depression. Establishing genome resource banks to conserve the genetic status of wild animals will provide a critical interface between ex-situ and in-situ conservation strategies. Cryopreservation of gonads effectively lengthens the genetic lifespan of individuals in a breeding program even after their death and contributes towards germplasm conservation of prized animals. Although the studies on domestic animals are quite promising, there are limitations for developing cryopreservation strategies in wild animals. In this review, we discuss different options for gonadal tissue cryopreservation with respect to humans and to laboratory, domestic, and wild animals. This review also covers recent developments in gonadal tissue cryopreservation and transplantation, providing a systematic view and the advances in the field with the possibility for its application in fertility preservation and for the conservation of germplasm in domestic and wild species.

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Section: Autografting Of Gonadal Tissuesmentioning

confidence: 99%