2004
DOI: 10.1055/s-2004-821078
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Abstract: Autologous fibrin glue re-enforced by autologous platelets can be safely produced in the operating room in a large volume, with an comparable efficacy at a lower cost than commercial sealants.

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Cited by 16 publications
(12 citation statements)
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References 14 publications
(15 reference statements)
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“…Clearly, they can provide these two functions together in many procedures such as intracranial 16 and spinal surgery, 17,18 duraplasty, 19 tumour resection, 20 aneurysm repair 21 and nerve anastomosis. 22 In cardiovascular surgery, fibrin sealants have been used successfully for bypass surgery, 23 vascular graft, 24 sinus rupture 25 and repair of septal defects. 26 Optimal application requires a dry operative field, which is often difficult to achieve and thus fibrin sealants are usually used prophylactically while the suture line is dry to prevent possible haemorrhage.…”
Section: Fibrin Gluesmentioning
confidence: 99%
“…Clearly, they can provide these two functions together in many procedures such as intracranial 16 and spinal surgery, 17,18 duraplasty, 19 tumour resection, 20 aneurysm repair 21 and nerve anastomosis. 22 In cardiovascular surgery, fibrin sealants have been used successfully for bypass surgery, 23 vascular graft, 24 sinus rupture 25 and repair of septal defects. 26 Optimal application requires a dry operative field, which is often difficult to achieve and thus fibrin sealants are usually used prophylactically while the suture line is dry to prevent possible haemorrhage.…”
Section: Fibrin Gluesmentioning
confidence: 99%
“…Therefore, the enhancement of wound, tissue and bone healing by local administration of concentrated autologous PLTs as a source of growth factors has been used in a wide variety of surgical settings. Platelets have been applicated locally in complicated cardiac procedures [10] and in spinal fusion surgery [11] as well as in plastic, reconstructive and cosmetic surgery [12,13]. Recently, the local administration of concentrated autologous PLTs, also called platelet‐rich plasma (PRP), has been applied to increase bone formation in combination with different bone regeneration materials for alveolar crest augmentation [14–22] and for the treatment of large bone defects of other localizations [23,24].…”
Section: Introductionmentioning
confidence: 99%
“…14 The strength of PRP adhesiveness was reported to be satisfactory in non-ophthalmic surgical investigations. [15][16][17][18][19] In our study, the clinically and histologically successful outcomes constituted signs of Figure 4 Image analysis of SMA immunostaining in the stroma of untreated corneas (a) and treated corneas in group P and S 90 days postsurgery. (a and b) SMA immunostaining in group P is similar to that found on a normal cornea (c) an evident difference is seen in group S. The measurements were made by quantitative densitometry and the data are shown as the mean ± SEM.…”
Section: Eyementioning
confidence: 67%
“…It can be used in very small surgical areas and interfaces because of its easy handling. PRP has an extraordinary strength and it has been used in patients by dentists, 15 oral maxillofacial surgeons, 16 plastic surgeons, 17 cardiovascular surgeons, 18 and otorhinolaryngologists. 19 Recently, ophthalmological publications refer to PRP used in dry eye treatment 20 and corneal ulcers healing.…”
Section: Introductionmentioning
confidence: 99%