Autologous chondrocyte implantation for full thickness articular cartilage defects of the knee

Abstract

Autologous chondrocyte implantation for full thickness articular cartilage defects of the knee.

Arthroscopic Mechanical Chondroplasty of the Knee Is Beneficial for Treatment of Focal Cartilage Lesions in the Absence of Concurrent Pathology

“…Along with a larger cohort, additional follow-up intervals and a longer total follow-up period may elucidate trends in patient-reported outcomes not captured at an average 31-month follow-up. Specifically, more invasive cartilage repair and restoration procedures such as microfracture and autologous chondrocyte implantation show gradual improvement in PROs over the first few years followed by a subsequent plateau or decline, 19 which are trends not afforded by the current study design.…”

Arthroscopic Mechanical Chondroplasty of the Knee Is Beneficial for Treatment of Focal Cartilage Lesions in the Absence of Concurrent Pathology

“…Along with a larger cohort, additional follow-up intervals and a longer total follow-up period may elucidate trends in patient-reported outcomes not captured at an average 31-month follow-up. Specifically, more invasive cartilage repair and restoration procedures such as microfracture and autologous chondrocyte implantation show gradual improvement in PROs over the first few years followed by a subsequent plateau or decline, 19 which are trends not afforded by the current study design.…”

Autologous chondrocyte implantation for the treatment of chondral and osteochondral defects of the talus: a meta‐analysis of available evidence

“…The overall Coleman Score to address quality of the individual studies in the present meta‐analysis was 65 points, which is below the study quality of recent ACI studies in the knee [5, 48, 49]. Nevertheless, some studies reach a satisfying Coleman Score of more than 70 points [3, 12, 27, 35, 42].…”

Osteochondral transplantation using autografts from the upper tibio‐fibular joint for the treatment of knee cartilage lesions

“…Furthermore, osteochondral lesions in different joint compartments were included and an inherent bias should be considered. In terms of cost‐effectiveness profile, it is not clear up to now which is the most efficient approach to symptomatic osteochondral lesions [38], and this issue was also not addressed in the present study. Meanwhile, mosaicplasty is a reproducible approach to provide hyaline cartilage coverage to full thickness defects in osteochondral transplantation.…”

Arthroscopic Mechanical Chondroplasty of the Knee Is Beneficial for Treatment of Focal Cartilage Lesions in the Absence of Concurrent Pathology

“…Along with a larger cohort, additional follow-up intervals and a longer total follow-up period may elucidate trends in patient-reported outcomes not captured at an average 31-month follow-up. Specifically, more invasive cartilage repair and restoration procedures such as microfracture and autologous chondrocyte implantation show gradual improvement in PROs over the first few years followed by a subsequent plateau or decline, 19 which are trends not afforded by the current study design.…”

Autologous chondrocyte implantation for the treatment of chondral and osteochondral defects of the talus: a meta‐analysis of available evidence

“…The overall Coleman Score to address quality of the individual studies in the present meta‐analysis was 65 points, which is below the study quality of recent ACI studies in the knee [5, 48, 49]. Nevertheless, some studies reach a satisfying Coleman Score of more than 70 points [3, 12, 27, 35, 42].…”

Osteochondral transplantation using autografts from the upper tibio‐fibular joint for the treatment of knee cartilage lesions

“…Furthermore, osteochondral lesions in different joint compartments were included and an inherent bias should be considered. In terms of cost‐effectiveness profile, it is not clear up to now which is the most efficient approach to symptomatic osteochondral lesions [38], and this issue was also not addressed in the present study. Meanwhile, mosaicplasty is a reproducible approach to provide hyaline cartilage coverage to full thickness defects in osteochondral transplantation.…”

Arthroscopic Mechanical Chondroplasty of the Knee Is Beneficial for Treatment of Focal Cartilage Lesions in the Absence of Concurrent Pathology

“…Along with a larger cohort, additional follow-up intervals and a longer total follow-up period may elucidate trends in patient-reported outcomes not captured at an average 31-month follow-up. Specifically, more invasive cartilage repair and restoration procedures such as microfracture and autologous chondrocyte implantation show gradual improvement in PROs over the first few years followed by a subsequent plateau or decline, 19 which are trends not afforded by the current study design.…”

Autologous chondrocyte implantation for the treatment of chondral and osteochondral defects of the talus: a meta‐analysis of available evidence

“…The overall Coleman Score to address quality of the individual studies in the present meta‐analysis was 65 points, which is below the study quality of recent ACI studies in the knee [5, 48, 49]. Nevertheless, some studies reach a satisfying Coleman Score of more than 70 points [3, 12, 27, 35, 42].…”

Osteochondral transplantation using autografts from the upper tibio‐fibular joint for the treatment of knee cartilage lesions

“…Furthermore, osteochondral lesions in different joint compartments were included and an inherent bias should be considered. In terms of cost‐effectiveness profile, it is not clear up to now which is the most efficient approach to symptomatic osteochondral lesions [38], and this issue was also not addressed in the present study. Meanwhile, mosaicplasty is a reproducible approach to provide hyaline cartilage coverage to full thickness defects in osteochondral transplantation.…”