Aural Changes in the Embryo of a Diabetic Mother

Effect of Gestational Diabetes Mellitus on Newborn Hearing: A Systematic Review

“…Studies have reported that poor gestational glycemic control can cause vascular damage in the developing inner ear. 25 , 26 Furthermore, 1 more study suggested that increased insulin-like growth factor-1 can modify cochlear morphogenesis. 27 Children with diabetic pregnancies were more likely to have high-frequency hearing loss with a severity of moderate to profound and sensorineural in nature.…”

Ear anomalies and hearing loss in patients with VACTERL association and the effect of maternal diabetes

“…This association might be linked to the There is evidence of an association between microtia and diabetes, independent of the context of VACTERL (Correa et al, 2008;Mastroiacovo et al, 1995;Van Bennekom et al, 2013), and diabetes has been shown to be associated with increased risk of HL (Lee et al, 2020;Padmadasan et al, 2022;Sharma et al, 2023;Tsao et al, 2023). Although the pathogenicity of diabetes in hearing impairment is not well understood, some studies proposed vascular disruption as a possible mechanism (Kelemen, 1955(Kelemen, , 1960.…”

Is gestational diabetes a risk factor for neonatal hearing loss?

“…Kelemen evaluated the results of histopathological analysis of specimens collected from a woman with severe gestational diabetes whose pregnancy was terminated during the second trimester. In this evaluation, it was determined that temporal bone development was normal, but there were bleeding spots on the cochlea and vestibulocochlear nerve [17]. None of the babies born from the mothers having gestational diabetes who were included in the study had any additional complication.…”