Atypical Endoscopic Features of Rectal Carcinoids

Shim, Ki–Nam; Yang, Suk‐Kyun; Myung, Seung‐Jae; Chang, Hye-Sook; Jung, Sung-Jin; Choe, Jun-Ho; Lee, Y. J.; Byeon, Jeong‐Sik; Lee, J. H.; Jung, Hwoon Yong; Hong, Weon‐Seon; Kim, J.-H.; Min, Young Il

doi:10.1055/s-2004-814202

Cited by 67 publications

(73 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In a Korean study, rectal NETs were discovered in 67 patients out of a total of 86,918 patients who underwent endoscopy between 1989 and 2002 (0.08%; ref. 15). However, this study included individuals who underwent endoscopy for anything other than screening purposes.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Risk Factors Associated with Rectal Neuroendocrine Tumors: A Cross-Sectional Study

Jung¹,

Yun

Chang

et al. 2014

Cancer Epidemiology, Biomarkers &Amp; Prevention

View full text Add to dashboard Cite

Background: The incidence of rectal neuroendocrine tumors (NET) has been increasing since the implementation of the screening colonoscopy. However, very little is known about risk factors associated with rectal NETs. We examined the prevalence of and the risk factors for rectal NETs in a Korean population.Methods: A cross-sectional study was performed on 62,171 Koreans who underwent screening colonoscopy. The clinical characteristics and serum biochemical parameters of subjects with rectal NET were compared with those of subjects without rectal NET using multivariate logistic regression.Results: Of a total of 57,819 participants, 101 [OR, 0.17%; 95% confidence interval (CI), 0.14-0.20] had a rectal NET. Young age (<50 years; OR, 2.09; 95% CI, 1.06-4.15), male gender (OR, 1.92; 95% CI, 1.15-3.20), alcohol drinking [adjusted OR (AOR), 1.56; 95% CI, 1.01-2.42], and a low high-density lipoprotein-cholesterol (HDL-C) level (AOR, 1.85; 95% CI, 1.10-3.11) were independent risk factors for rectal NETs. Cigarette smoking, fatty liver, metabolic syndrome, higher triglyceride level (!150 mg/dL), and higher homeostasis model assessment of insulin resistance (!2.5) were not independently associated with rectal NETs, although these factors were more common in individuals with rectal NETs in the univariate analysis.Conclusions: Young age (<50 years), male gender, alcohol drinking, and a low HDL-C level were risk factors for rectal NETs. Our results suggest that gender, behavioral factors, and dyslipidemia may affect the risk for developing rectal NETs.Impact: The findings of this study contribute to a better understanding of the influence of gender, behavioral factors, and dyslipidemia in developing rectal NETs. Cancer Epidemiol Biomarkers Prev; 23(7); 1406-13. Ó2014 AACR.

show abstract

Section: Discussionmentioning

confidence: 99%

“…13,18,19). The male predominance of rectal NETs appears to be more pronounced in Asian populations (13,15,19). There may be differences in susceptibility to rectal NET development between genders according to ethnic group.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors Associated with Rectal Neuroendocrine Tumors: A Cross-Sectional Study

Jung¹,

Yun

Chang

et al. 2014

Cancer Epidemiology, Biomarkers &Amp; Prevention

View full text Add to dashboard Cite

show abstract

“…They are nodules with a wide base, smooth at the surface, covered by a mucosa of normal appearance, or slightly yellow/white [5][6][7][8][9]. Atypical features (observed in 20%) include: semi-pedunculated shape, reddening of the mucosa, central depression, erosion or ulceration on the surface.…”

Section: Endoscopic Diagnosticsmentioning

confidence: 99%

Nowotwory neuroendokrynne jelita grubego — zasady postępowania (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)

Starzyńska

Deptała

Królicki

et al. 2014

Endokrynologia Polska

View full text Add to dashboard Cite

Neuroendocrine neoplasms of the large intestine account for 20% of all neuroendocrine neoplasms (NENs) and are most commonly found in the rectum. The rate of detection of colorectal NENs is increasing, and this tendency will continue due to the widespread use of colonoscopy as a screening tool and the removal of all diagnosed lesions. This paper provides updated guidelines for the management of patients with colorectal NENs. Recent data on epidemiology, clinical characteristics, biochemical, and pathomorphological diagnosis as well as useful imaging techniques are presented. We look in detail at novel methods of treatment including endoscopic and surgical management, pharmacological and radioisotope therapy. We summarise monitoring of the treatment. (Endokrynol Pol 2013; 64 (6): 494-504)

show abstract

“…Other reports have stated that the tendency for metastatic spread was associated with tumor size, histopathological differentiation, muscular invasion, and lymphovascular invasion [7,20]. Among these factors, tumor size was a simple and reliable indicator for risk of metastatic involvement, which occurred in 3% of tumors with <10 mm diameter [7,20]. Konishi et al have reported prognosis and risk factors of metastasis in colorectal carcinoids [21].…”

Section: Discussionmentioning

confidence: 97%

Efficacy of Endoscopic Mucosal Resection after Circumferential Mucosal Incision of Small Rectal Carcinoid Tumors

Andoh¹

2011

J Gastrointest Digest Sys

View full text Add to dashboard Cite

Background: Endoscopic mucosal resection is widely used for treating rectal carcinoid tumors. However, histopathology has revealed that submucosal invasion leads to incomplete resection. Endoscopic submucosal dissection, which enables en bloc resection regardless of tumor size, has recently been reported to be useful in treating rectal carcinoid tumors; however, it is not widely used as standard treatment because of technical demands. We use endoscopic mucosal resection after circumferential mucosal incision, which is performed after mucosal resection around the lesion to treat rectal carcinoid tumors. To our knowledge, this is the first report of endoscopic mucosal resection after circumferential mucosal incision for colorectal carcinoid tumors.

show abstract

Atypical Endoscopic Features of Rectal Carcinoids

Abstract: Atypical endoscopic appearances of rectal carcinoids are observed more frequently as the size of the tumor increases and a finding of ulceration may have a prognostic value.

Cited by 67 publications

References 7 publications

Risk Factors Associated with Rectal Neuroendocrine Tumors: A Cross-Sectional Study

Risk Factors Associated with Rectal Neuroendocrine Tumors: A Cross-Sectional Study

Nowotwory neuroendokrynne jelita grubego — zasady postępowania (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)

Efficacy of Endoscopic Mucosal Resection after Circumferential Mucosal Incision of Small Rectal Carcinoid Tumors

Contact Info

Product

Resources

About