Atypical Early Follicular Graft-vs-Host Disease

Many faces of graft‐versus‐host disease

“…Follicular involvement has been described in patients with lichenoid cGvHD; 10 however, it has also been seen in the early phases of patients with sclerodermatous GvHD 30 (Fig. 5).…”

“…Dermatologists have traditionally used this classification, 4 but multiple findings suggest this may no longer be suitable. It is possible to find aGvHD lesions beyond day 100, 8 while cGvHD lesions sometimes appear before 4,9,10 . Histological findings of aGvHD can be found in biopsies performed beyond day 100 and lichenoid findings in biopsies performed before day 100 11 .…”

Coexistence of Eccrine Squamous Syringometaplasia and Graft-Versus-Host Disease in a Patient with Secondary Myelodysplastic Syndrome

“…With respect to acute GVHD, until 2003 no case of coexis tence of both processes had been described, and it was even suggested that the appearance of ESS could be a diagnostic key to distinguish between a chemotherapy induced medicinal reaction and acute GVHD (7). As well as the rarity of finding symptoms of ESS in a patient with acute GVHD, our case has other unusual characteristics, such as the early appearance of lesions and marked follicular distribution, which could cor respond to an infrequent form described as follicular variant in acute and chronic GVHD (8,9).…”

Enfermedad de injerto contra huésped, una presentación inusual

“…En la literatura científica se han reportado presentaciones atípicas de esta enfermedad, tanto en la forma aguda como en la crónica (8) . Se han descrito manifestaciones como hiperpigmentación, lesiones psoriasiformes (9,10) y placas liquenoides foliculares (11) o del tipo de la dermatitis de contacto (12) . En el presente caso, la afectación de la piel y del sistema gastrointestinal (diarrea hipersecretora) es clásica de la enfermedad; sin embargo, es atípica la afección cutánea, por la hiperpigmentación de las mejillas y la nariz.…”