2011
DOI: 10.1590/s1806-37132011000600016
View full text |Buy / Rent full text
|
Sign up to set email alerts
|

Abstract: As vasculites antineutrophil cytoplasmic antibody (ANCA, anticorpo anticitoplasma de neutrófilos) associadas (VAAs) são caracterizadas por uma inflamação sistêmica das artérias de pequeno e médio calibre (especialmente no trato respiratório superior e inferior, e nos rins). As VAAs compreendem a granulomatose de Wegener (agora chamada de granulomatose com poliangeíte), poliangeíte microscópica, VAA limitada ao rim e a síndrome de Churg-Strauss. Neste artigo, discutiremos as fases de tratamento dessas vasculite… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
8
0

Year Published

2013
2013
2015
2015

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 7 publications
(8 citation statements)
references
References 19 publications
(8 reference statements)
0
8
0
Order By: Relevance
“…Primary AAV is not a disease but a group of diseases. c-ANCA and its target antigen PR3-ANCA are more frequently observed in patients with GPA, while p-ANCA and its target antigen MPO-ANCA are more frequently observed in patients with MPA and EGPA (3). In the present study, the total number of patients with MPA and patients with EGPA was 41 while the number of GPA patients was 7.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Primary AAV is not a disease but a group of diseases. c-ANCA and its target antigen PR3-ANCA are more frequently observed in patients with GPA, while p-ANCA and its target antigen MPO-ANCA are more frequently observed in patients with MPA and EGPA (3). In the present study, the total number of patients with MPA and patients with EGPA was 41 while the number of GPA patients was 7.…”
Section: Discussionmentioning
confidence: 99%
“…Primary vasculitis is a systemic disease of unknown etiology (1–3). The main pathological features are vascular wall inflammation and fibrinoid necrosis.…”
Section: Introductionmentioning
confidence: 99%
“…Two immunofluorescence patterns are observed – cytoplasmic (cANCA) and perinuclear (pANCA). In humans the presence of cANCA appears highly correlated with detection of antibodies against proteinase 3 by ELISA, whilst the presence of pANCA is correlated with detection of antimyeloperoxidase antibodies on ELISA (Ozaki 2007 ; Santana et al 2011 ). Whilst cANCA are highly specific for GPA and are present in at least 90% of affected people, pANCA are less specific and only detected in around 10% of humans with GPA (Ozaki 2007 ; Pagnoux & Wolter 2012 ; Santana et al 2011 ).…”
Section: Discussionmentioning
confidence: 99%
“…In humans the presence of cANCA appears highly correlated with detection of antibodies against proteinase 3 by ELISA, whilst the presence of pANCA is correlated with detection of antimyeloperoxidase antibodies on ELISA (Ozaki 2007 ; Santana et al 2011 ). Whilst cANCA are highly specific for GPA and are present in at least 90% of affected people, pANCA are less specific and only detected in around 10% of humans with GPA (Ozaki 2007 ; Pagnoux & Wolter 2012 ; Santana et al 2011 ). The only ANCA assay currently validated for use in dogs, to the authors’ knowledge, is the immunofluorescent pANCA assay set up by the Royal Veterinary College to study inflammatory bowel disease in dogs, but the antigen the anti-dog IgG antibodies bind to has not been identified in dogs (Allenspach et al 2004 ).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation