Attempts to Isolate a Virus From Pemphigus Foliaceus Cases

Angulo, Juan J.

doi:10.1001/archderm.1954.01540160074010

Cited by 21 publications

(1 citation statement)

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“…For many years, it was assumed that viral infection, especially Herpes virus may have role in induction or exacerbation of pemphigus patients. Physicians have tried to find virus in blood and mucocutaneous lesions of pemphigus patients (1)(2)(3). Several previous studies reported that viral infections including Herpes simplex virus (HSV), Varicella zoster virus (VZV), Epstein-Barr virus (EBV), Cytomegalovirus (CMV), Human Herpes virus 8 (HHV 8) and Human Immunodeficiency virus (HIV) may have trigger role in activation or exacerbation of pemphigus.…”

Section: Introductionmentioning

confidence: 99%

Association of HSV1/2 Infection and Pemphigus Disease

Rahmati-Roodsari

Rahmdar

Alfaragi

et al. 2013

Arch Pediatr Infect Dis

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Background: Pemphigus is known as an autoimmune bullous disease of the skin and mucous membranes that is relatively prevalent in Iran. The herpes virus is one of the suspected factors that might have role in induction or exacerbation of pemphigus. Objectives: Present study was performed to assess the prevalence of HSV1/2 infection in pemphigus patients referred to Shohadae-Tajrish and Loghman-e-Hakim hospitals during 2010-2011. Patients and Methods: Forty pemphigus patients enrolled in the study. A lesional skin or mucosal biopsy was taken from each patient and analyzed by PCR for detection of HSV1/2. The PCR results were positive or negative, and then the frequency of HSV1/2 infections in pemphigus patients was calculated. Results: Ten patients (25%) had a history of orolabial herpes infection. The results of all samples were negative for HSV1 except one sample which showed the positive result for HSV2 in a patient with history of herpes infection. He was considerably resistant to treatment pemphigus vulgaris with about 60 skin lesions and 20 mucosal lesions. Adding Acyclovir to his treatment regime for ten days resulted in full recovery. Conclusions: Prevalence of HSV1/2 in mucocutaneous biopsies from pemphigus patients is 2.5% and possibly HSV1/2 has no role in the pathogenesis of pemphigus lesions. But resistant cases to treatment might be suspected to HSV.

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Section: Introductionmentioning

confidence: 99%

Association of HSV1/2 Infection and Pemphigus Disease

Rahmati-Roodsari

Rahmdar

Alfaragi

et al. 2013

Arch Pediatr Infect Dis

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Excision of a carcinoma of the middle third of the œsophagus with aortic graft replacement—preliminary report

1957

British Journal of Surgery

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Two and a half years' survival of a grafted abdominal aortic aneurysm with histological studies

Shucksmith

Mitchell

Zinnemann

1958

British Journal of Surgery

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ONE of our male patients with an abdominal aortic aneurysm treated by excision, endarterectomy, and insertion of a freeze-dried homograft died two and a half years later from coronary thrombosis. We have been unable to find any reference in the literature these areas were not affected by the freeze-drying process which was used to preserve the graft.Externally at autopsy the graft appeared like a new vessel, and the area of the aorta which had been endarterectomized looked very much healthier than FIG. r7r.-The post-mortem specimen showing the satisfactory result 21 years after the replacement of the distal portion and bifurcation of the aorta by a homograft. ( x 2.)to a patient surviving more than one year after the insertion of a similar graft.At operation, failure to wash out any soft clot before the end of the grafting procedure delayed restoration of the peripheral pulses, but probably had no permanent ill effects. During the period of survival we were able to watch the change in the patient's peripheral pulses as he developed intermittent claudication; finally we have detailed histological studies of his vessels and of the graft.Areas of atheroma were present in the graft when it was taken from a man aged 39, and apparently FIG. 17z.--Distal portion of graft showing the lines of anastomosis in the common iliac arteries (A). The plaques of atheroma (6) which are present in the graft are not so severe as those in the patient's arteries. ( x 4.)

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Attempts to Isolate a Virus From Pemphigus Foliaceus Cases

Cited by 21 publications

References 1 publication

Association of HSV1/2 Infection and Pemphigus Disease

Association of HSV1/2 Infection and Pemphigus Disease

Excision of a carcinoma of the middle third of the œsophagus with aortic graft replacement—preliminary report

Two and a half years' survival of a grafted abdominal aortic aneurysm with histological studies

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