2019
DOI: 10.1111/jdv.15642
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Background Data regarding the association between atopic dermatitis (AD) and the metabolic syndrome are controversial. Objective To evaluate the prevalence of the metabolic syndrome and its components in a large group of patients with AD compared to a matched reference group. Methods A cross‐sectional study of AD patients diagnosed by a dermatologist between 1998 and 2016, and a matched comparison group was performed. We analysed the association between AD and metabolic syndrome, its components and possible co… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

1
58
0
1

Year Published

2019
2019
2023
2023

Publication Types

Select...
10

Relationship

1
9

Authors

Journals

citations
Cited by 38 publications
(60 citation statements)
references
References 17 publications
1
58
0
1
Order By: Relevance
“…Psychiatric and psychological disorders, especially attention deficit hyperactivity disorder (ADHD), depression, or anxiety, are also more frequent in AD patients, possibly due to pruritus-induced lack of sleep, psychological stress, and high levels of proinflammatory cytokines [9]. Other comorbidities of varying nature such as cardiovascular diseases, type 2 diabetes, obesity, infections that go beyond cutaneous over-infection, malignancies (e.g., lymphomas), or autoimmune disorders (e.g., alopecia areata, lupus erythematosus, and inflammatory bowel disease) are also somehow linked to AD [12,[14][15][16]. To the best of our knowledge, there are no large-scale population-based publications specifically analyzing the global comorbidity of AD during childhood.…”
Section: Introductionmentioning
confidence: 99%
“…Psychiatric and psychological disorders, especially attention deficit hyperactivity disorder (ADHD), depression, or anxiety, are also more frequent in AD patients, possibly due to pruritus-induced lack of sleep, psychological stress, and high levels of proinflammatory cytokines [9]. Other comorbidities of varying nature such as cardiovascular diseases, type 2 diabetes, obesity, infections that go beyond cutaneous over-infection, malignancies (e.g., lymphomas), or autoimmune disorders (e.g., alopecia areata, lupus erythematosus, and inflammatory bowel disease) are also somehow linked to AD [12,[14][15][16]. To the best of our knowledge, there are no large-scale population-based publications specifically analyzing the global comorbidity of AD during childhood.…”
Section: Introductionmentioning
confidence: 99%
“…Outcomes were also adjusted for metabolic syndrome, owing to its established triggering effect in gout [ 11 ]. Metabolic syndrome was defined as the presence of at least three of the following conditions: type 2 diabetes mellitus, dyslipidemia, hypertension, or obesity [ 12 ], as was previously demonstrated [ 13 ]. Smoking status was classified as either current smoker or never/past smoker.…”
Section: Methodsmentioning
confidence: 99%
“…MS is implicated as an important risk factor for type 2 diabetes mellitus and cardiovascular disease and has therefore attracted increasing attention in recent years. Growing evidence has shown that some dermatological diseases such as psoriasis [6] alopecia areata [7], hidradenitis suppurativa [8], atopic dermatitis [9] and vitiligo [10] are associated with a high prevalence of MS compared with the general population. LP and psoriasis show a similar pathological background, including features of skin barrier dysfunction [11], T lymphocyte activation, and upregulation of cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-10, and IL-4 [12] and may therefore be associated with a high risk of MS.…”
Section: Introductionmentioning
confidence: 99%