2015
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Abstract: RESUMORhodococcus equi é o agente etiológico da rodococose equina, importante doença respiratória de potros. Especialmente na última década, a emergência de cepas resistentes aos antimicrobianos empregados no tratamento da rodococose tem sido relatada. Nesse sentido, há a necessidade de estudos envolvendo terapias alternativas e novas tecnologias, incluindo o uso de plantas medicinais e nanotecnologia. Neste trabalho utilizou-se Melaleuca alternifolia nas seguintes formulações: óleo livre, nanocápsula, nanoemu… Show more

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Cited by 14 publications
(7 citation statements)
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References 17 publications
(7 reference statements)
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“…Sagave et al . (2015) studied the antimicrobial activity of TTO against a Rhodococcus equi isolate, and reported that the activity of the oil was enhanced when used as nanoformulation. Nanotechnology is an important feature of the pharmaceutical industry, especially in the development of more efficient formulations that can remain for long periods at the action site (Putheti et al .…”
Section: Discussionmentioning
confidence: 99%
“…9 One of the possible benefits of using nanostructures is the decrease of the concentration in the formulation, presenting equal or greater effect than the usual formulation, as previously demonstrated with chlorhexidine nanocapsules 19,54 and vegetable oil. 15 Consequently, our group decided to compare a lowconcentrated nanostructured formulation to a consolidated formulation, resulting in similar effects both for NM-Cl and for CS-Cl, demonstrating that the use of nanoformulations could decrease chlorhexidine concentrations.…”
Section: In Vivo Assaymentioning
confidence: 99%
“…14 Increasing reports of resistance to chlorhexidine formulation are the main reason to the current demand of the investigation of antiseptic alternatives. Nanostructured formulations are believed to be an alternative for hospital antiseptics, 7,14,15 and among them, the nanoemulsions are heterogeneous dispersions of immiscible liquids in droplet form, stabilized by interfacial surfactant film usually in combination with surfactant molecules. [17][18][19][20][21][22][23][24][25][26][27][28][29] Nanoparticles have been widely studied as potential carriers for antimicrobials, and some advantages compared to conventional antibacterials are: the contour to the resistance mechanisms, mainly due to the size, as it results in a greater interaction due to the surface area; impediment of biofilm formation; targeting to the site of infection and consequently, minimizing side effects; controlled and sustained release and association of antimicrobials in a single nanoparticulate system.…”
Section: Introductionmentioning
confidence: 99%
“…The chemical components of essential oils (EOs) from medicinal plants have antibacterial (Sagave et al . ), antifungal (Cleff et al . ,b) and antiparasitic (Santos et al .…”
Section: Introductionmentioning
confidence: 99%
“…The chemical components of essential oils (EOs) from medicinal plants have antibacterial (Sagave et al 2015), antifungal (Cleff et al 2010a,b) and antiparasitic (Santos et al 2012) properties, and they act as insect repellents (Lee et al 2007). Moreover, previous studies have reported Pythium spp.…”
Section: Introductionmentioning
confidence: 99%