At the crossroads of oral facial genetics

Marković, Milan

doi:10.1093/ejo/14.6.469

Cited by 56 publications

(34 citation statements)

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“…The inheritance of malocclusion is influenced by genetic and environmental factors, but with a greater emphasis on the influence of environment, in particular, the orofacial tissues [18][19][20][21]. The positioning of the soft tissues and the tongue posture has a prime role in determining the positioning of the teeth and it is also a determiner of bone formation.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Lingual Frenulum Lengths in Skeletal Malocclusion

Meenakshi

Jagannathan

2014

JCDR

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Section: Discussionmentioning

confidence: 99%

Assessment of Lingual Frenulum Lengths in Skeletal Malocclusion

Meenakshi

Jagannathan

2014

JCDR

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“…Since the triplets in the study 21 were confirmed to be genetically monozygotic, they concluded that the triplets demonstrated non-genetic variation in the expression of familial hypodontia. Another report 18 demonstrated concordance for hypodontia and/or hypoplasia of the maxillary lateral incisors in monozygotic members and discordance in dizygotic members in twins and triplets studies which strongly indicated a dominant genetic aetiology. These reports described cases of mild hypodontia, the extent of which does not compare with the severity of our cases.…”

Section: Discussionmentioning

confidence: 95%

“…[16][17][18][19] Three articles on hypodontia in triplets 18,20,21 were found using a PubMed search and none described hypodontia of the severity seen in the patients in this case report. This article describes a case involving a set of triplets with severe hypodontia, affecting molars, premolars and incisors.…”

Section: Verifiable Cpd Papermentioning

confidence: 99%

Severe hypodontia in a set of triplets

et al. 2006

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Hypodontia is the developmental absence of one or more teeth from the dentition and constitutes one of the most common developmental anomalies in humans with a reported prevalence of 1.6 to 9.6% in the permanent dentition. Hypodontia may occur in association with other genetic diseases, or as an isolated familial or sporadic form. This article describes the rare phenomenon of severe hypodontia in a set of triplets. The triplets presented with congenital absence of the second molars, second premolars in all quadrants and lower central incisors. An additional five teeth (upper canines, upper lateral incisors and upper left first premolar) were missing in one of the triplets. The treatment plan and the possible genetic mode of inheritance are discussed.

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“…In one study carried out by Milne and Cleall 22 , it is suggested that the maxillary incisors follow the same eruptive axis before and after emerging into the oral cavity, with the eruptive pathway depending on the axial inclination of tooth buds. Markovic's study 23 on twins and triplets is important, as the author not only registered a concordance for the Class II Division 2 malocclusion between monozygotic twins but also a similarity with regard to the incisor position. A deep knowledge of the processes involved in the pre-and post-eruptive tooth pathway could be decisive for a better understanding of the incisor retroclination mechanism in Class II Division 2 malocclusion.…”

Section: Discussionmentioning

confidence: 99%