Abstract:Asymmetric epoxidation of olefins has been proven to be one of the most important methods to generate chiral epoxides, which are highly useful intermediates in the stereoselective synthesis of biologically interesting compounds. In this chapter, several powerful and practical asymmetric epoxidation methods and their utilities for the stereoselective synthesis of drug substances and natural products are described. The representative asymmetric epoxidation methods that are described in the chapter include direct… Show more
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