Astaxanthin attenuates glucose-induced liver injury in largemouth bass: role of p38MAPK and PI3K/Akt signaling pathways
Zhihong Liao,
Xuanshu He,
Anqi Chen
et al.
Abstract:Background
Astaxanthin (ASX) has been documented to exert beneficial influence on various processes in fish. Largemouth bass serves as a common model for studying glucose-induced liver disease, making it imperative to investigate the regulatory mechanisms underlying its liver health.
Methods
Largemouth bass were fed with a control diet (CON), a high carbohydrate diet (HC), or a HC diet supplemented astaxanthin (HCA) for 8-weeks, followed by the glucose tolerance test (GTT). Primary hepatocytes were treated wit… Show more
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