Association of osteoporosis and bone medication with the periodontal condition in elderly women

Penoni, Daniela Cia; Torres, Sandra Regina; Farias, Maria Lúcia Fleiuss; Fernandes, Tatiana; Luiz, Ronir Raggio; Leão, Anna Thereza Thomé

doi:10.1007/s00198-015-3437-y

Cited by 46 publications

(53 citation statements)

References 40 publications

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“…Overall, 18 (66%) of the 27 included studies had low or moderate risk of bias (Figure ). Figure shows the analysis for the risk of bias exclusively for observational studies.…”

Section: Resultsmentioning

confidence: 99%

“…Longitudinal studies presented the lowest overall risk of bias. Among the cross‐sectional studies, only 4 (30.7%) had a low risk of bias. The 3 interventional studies included were deemed to have a low risk of bias (Figure ).…”

Section: Resultsmentioning

confidence: 99%

“…The majority of the studies were conducted in the USA, whereas populations from Europe, South and North America and Asia were also assessed. Ten studies evaluated samples from the general population, 3 studies included only older men, 4 studies assessed exclusively post‐menopausal women and 2 included older women . Other studies evaluated patients with specific health conditions (pregnant women, hospital patients, breast cancer survivors, HIV‐infected adults, liver transplant patients) …”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Vitamin D levels and risk for periodontal disease: A systematic review

Pinto

Goergen

Muniz

et al. 2018

J of Periodontal Research

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“…Overall, 18 (66%) of the 27 included studies had low or moderate risk of bias (Figure ). Figure shows the analysis for the risk of bias exclusively for observational studies.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Vitamin D levels and risk for periodontal disease: A systematic review

Pinto

Goergen

Muniz

et al. 2018

J of Periodontal Research

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show abstract

“…Various systemic risk factors, such as genetics, age, sex, vitamin D deficiency, medical hormone therapy, diet, smoking, obesity, and physical activity, affects the development of osteoporosis [78,79], but several of these are also risk factors for PDIS [80]. Bone density changes throughout life, but after the menopause a decrease in estrogen production occurs, which seems to be associated with an increased risk of osteoporosis.…”

Section: Explanatory Modelsmentioning

confidence: 99%

Comorbidity of periodontal disease: two sides of the same coin? An introduction for the clinician

Holmstrup

Damgaard

Olsen

et al. 2017

Journal of Oral Microbiology

158

140

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Increasing evidence has suggested an independent association between periodontitis and a range of comorbidities, for example cardiovascular disease, type 2 diabetes, rheumatoid arthritis, osteoporosis, Parkinson’s disease, Alzheimer’s disease, psoriasis, and respiratory infections. Shared inflammatory pathways are likely to contribute to this association, but distinct causal mechanisms remain to be defined. Some of these comorbid conditions may improve by periodontal treatment, and a bidirectional relationship may exist, where, for example, treatment of diabetes can improve periodontal status. The present article presents an overview of the evidence linking periodontitis with selected systemic diseases and calls for increased cooperation between dentists and medical doctors to provide optimal screening, treatment, and prevention of both periodontitis and its comorbidities.

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“…Osteoporosis is considered a “modifiable risk factor” for periodontitis with regard to host modulation therapy [23•, 72••, 73]. Osteoporotic elderly women who were not treated for the condition have a higher risk for severe periodontal disease [74•]. …”

Section: Interdisciplinary Management Of Osteoporosis and Periodontitismentioning

confidence: 99%

Osteoporosis and Periodontitis

Wang

McCauley

2016

Curr Osteoporos Rep

151

124

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Osteoporosis and periodontitis are both diseases characterized by bone resorption. Osteoporosis features systemic degenerative bone loss that leads to loss of skeletal cancellous microstructure and subsequent fracture, whereas periodontitis involves local inflammatory bone loss, following an infectious breach of the alveolar cortical bone, and it may result in tooth loss. Most cross-sectional studies have confirmed the association of osteoporosis and periodontitis primarily on radiographic measurements and to a lesser degree on clinical parameters. Multiple shared risk factors include age, genetics, hormonal change, smoking, as well as calcium and vitamin D deficiency. Both diseases could also be risk factors for each other and have a mutual impact that requires concomitant management. Suggested mechanisms underlying the linkage are disruption of the homeostasis concerning bone remodeling, hormonal balance, and inflammation resolution. A mutual interventional approach is emerging with complex treatment interactions. Prevention and management of both diseases require interdisciplinary approaches and warrants future well-controlled longitudinal and interventional studies for evidence-based clinical guidelines.

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Association of osteoporosis and bone medication with the periodontal condition in elderly women

Abstract: Elderly women with osteoporosis have a greater chance to present periodontitis, with higher severity than those with normal BMD. Osteoporosis treatment provides protection for periodontitis.

Cited by 46 publications

References 40 publications

Vitamin D levels and risk for periodontal disease: A systematic review

Vitamin D levels and risk for periodontal disease: A systematic review

Comorbidity of periodontal disease: two sides of the same coin? An introduction for the clinician

Osteoporosis and Periodontitis

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