2013
DOI: 10.1093/ije/dyt198
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Abstract: Background Sub-Saharan Africa (SSA) has the highest burden of HIV in the world and a rising prevalence of cardiometabolic disease; however, the interrelationship between HIV, antiretroviral therapy (ART) and cardiometabolic traits is not well described in SSA populations.Methods We conducted a systematic review and meta-analysis through MEDLINE and EMBASE (up to January 2012), as well as direct author contact. Eligible studies provided summary or individual-level data on one or more of the following traits in … Show more

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Cited by 164 publications
(148 citation statements)
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References 91 publications
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“…Data from the 2014 South African National HIV Prevalence, Incidence and Behaviour Survey reported a national HIV prevalence of 12.2% [42] compared to 20.7% in the current study. The inverse association between HIV infection and BMI has been extensively reported [43], and confirmed by the results for both men and women in this study.…”
Section: Discussionsupporting
confidence: 92%
“…Data from the 2014 South African National HIV Prevalence, Incidence and Behaviour Survey reported a national HIV prevalence of 12.2% [42] compared to 20.7% in the current study. The inverse association between HIV infection and BMI has been extensively reported [43], and confirmed by the results for both men and women in this study.…”
Section: Discussionsupporting
confidence: 92%
“…The non-AIDS related mortality rates are largely attributable to cardiovascular disease (Farahani et al, 2016). Current hypotheses link the increased incidence of these comorbidities to side-effects of antiviral therapy (Dillon et al, 2013;El-Sadr, 2007), HIV-related chronic inflammation (Hearps et al, 2014) and modifiable lifestyle factors, such as increased tobacco use (Lifson and Lando, 2012) and decreased physical activity (Schuelter-Trevisol et al, 2012). There is evidence in PLWH that participation in physical activity might reduce cardio-metabolic risk factors and improve quality of life (Fillipas et al, 2010;Gomes-Neto et al, 2013;Leach et al, 2015;Neto et al, 2015;O'Brien et al, 2008).…”
Section: Introductionmentioning
confidence: 99%
“…Conversely, a meta-analysis comparing HIV-infected individuals from sub-Saharan Africa to individuals without HIV did not find any evidence of association between HIV infection and FBG. 31 …”
Section: Prevalence Of Dm Ifg and Dysglycemia Among Patients With Himentioning
confidence: 99%