2020
DOI: 10.21203/rs.3.rs-54000/v1
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Abstract: Background: Previous studies proved that AGT gene polymorphisms were associated with the serum lipids metabolism; however, it is not clear whether AGT rs2493132 increases the risk of NAFLD and CAD. This study was designed to investigate the relationship between AGT rs2493132 gene polymorphism and the developing risk of NAFLD and CAD in Chinese Han population.Methods: A total of 142 NAFLD patients, 109 NAFLD + CAD patients, and 246 health controls were included in this study. PCR method was used to measure AGT … Show more

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“…In patients with peripheral arterial disease, the association between AGT rs699 CC genotype and high-density lipoprotein (HDL) levels was proved to be significant [ 31 ]. The non-alcoholic fatty liver disease (NAFLD) patients with the AGT rs5051 TC + CC genotype had a significantly increased risk of coronary heart disease (CHD) in the northern Chinese Han population [ 32 ]. Nonetheless, the association between these three AGT SNPs and PE has not been well established.…”
Section: Discussionmentioning
confidence: 99%
“…In patients with peripheral arterial disease, the association between AGT rs699 CC genotype and high-density lipoprotein (HDL) levels was proved to be significant [ 31 ]. The non-alcoholic fatty liver disease (NAFLD) patients with the AGT rs5051 TC + CC genotype had a significantly increased risk of coronary heart disease (CHD) in the northern Chinese Han population [ 32 ]. Nonetheless, the association between these three AGT SNPs and PE has not been well established.…”
Section: Discussionmentioning
confidence: 99%