Association of Adenoid Surface Biofilm Formation and Chronic Otitis Media With Effusion

Abstract

In pediatric patients, adenoid surface biofilm formation may be associated with COME etiopathogenesis.

Diagnostic Accuracy of Nasopharyngeal Swabs in Detecting Biofilm‐Producing Bacteria in Chronic Adenoiditis

“…Kania et al 10 found a lower prevalence of mucosal biofilm (54% of 39 adenoids removed because of otological disease), but this may be due to the different detection methods used: spectrophotometry in our study and SEM and CLSM in theirs. On the other hand, our results are in line with those of Saylam et al, 24 who recently detected biofilm in all of the adenoidal samples taken from children with adenoidal hypertrophy with or without chronic middle ear effusion. These findings, together with those of a previous study by Coticchia et al, 2 who found that nearly 95% of the adenoidal surface of children with chronic rhinosinusitis is covered with biofilms, confirms the theory that the adenoidal mucosal surface acts as a reservoir for opportunistic BPB capable of interfering with potential pathogens and may be responsible for acute infectious exacerbations 10,21 .…”

Biofilm formation by bacteria isolated from upper respiratory tract before and after adenotonsillectomy

“…on adenoid tissue samples from children with adenoid hypertrophy and with those by Coticchia et al. who found biofilm in about 95% of children with chronic rhinosinusitis (24, 25).…”

Chronic Tonsillopharyngitis

“…A different study noted that the epithelial covering of the tonsils and adenoids of patients awaiting adenotonsillectomy for an indication of chronic tonsillitis or adenoiditis was frequently coated with a biofilm [11]. Similar biofilm formation has also been noted in a number of other diseases of the ear, nose and throat, namely chronic rhinosinusitis and chronic otitis media [12,13].…”