Association between use of tobacco and age on graying of hair

Sabharwal, Robin; Gupta, Atul; Moon, Ninad; Mahendra, Ashish; Sargaiyan, Vinod; Gupta, Alka; Subudhi, Santosh Kumar; Gupta, Shivangi

doi:10.4103/1117-6806.137308

Cited by 14 publications

(10 citation statements)

References 11 publications

(12 reference statements)

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“…Smoking [23][24][25][26][27] Smoking and the use of other tobacco products (e.g., gutka and straight chewing tobacco) were reported to be associated with PHG. 27…”

Section: Hair Loss 22mentioning

confidence: 99%

A review of the etiologies, clinical characteristics, and treatment of canities

2019

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Hair pigmentation is regulated by follicular melanogenesis, in which the process consists of melanin formation and transfer to keratinocytes in the hair shaft. Human hair follicles contain two types of melanin: the brown‐black eumelanin and yellow‐red pheomelanin. Eumelanin is commonly present in black and brown hair while pheomelanin is found in auburn and blonde hair. Hair follicle melanogenesis is under cyclical control and is concurrently coupled to hair growth. Many factors including intrinsic and extrinsic factors affect the follicular melanogenesis. Though many studies have been conducted to identify the pathogenesis and regulation of hair pigmentation, the etiology of canities and hair pigmentation is still unclear. The pathogenesis of canities or gray hair is believed to occur either from insufficient melanin formation due to melanocyte degeneration or a defect in melanosomal transfer. Canities is an aging sign which often interferes with one's socio‐cultural adjustment. On the other hand, premature canities correlate with diseases such as osteopenia and cardiovascular disease. Risk factors associated with canities are not only genetic but also external causes. For example, smoking, alcohol consumption, and stress are among the most common factors. Camouflage techniques are still used as the primary treatment of canities. Further treatments for canities are being developed to achieve the true reversal of hair pigmentation.

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“…Smoking [23][24][25][26][27] Smoking and the use of other tobacco products (e.g., gutka and straight chewing tobacco) were reported to be associated with PHG. 27…”

Section: Hair Loss 22mentioning

confidence: 99%

A review of the etiologies, clinical characteristics, and treatment of canities

2019

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“…In a relatively recent Indian study 29 , they noticed that with increasing age, the frequency of individuals with gray hair also increased. This could be explained on the basis that, with age, the production of free radicals increases, while the endogenous defense mechanisms decrease.…”

Section: Discussionmentioning

confidence: 95%

The degree of hair graying as an independent risk marker for coronary artery disease, a CT coronary angiography study

ElFaramawy

Hanna

Darweesh

et al. 2018

The Egyptian Heart Journal

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BackgroundCardiovascular disease is a leading cause of death worldwide. Aging is an unavoidable coronary risk factor and is associated with dermatological signs that could be a marker for increased coronary risk. We tested the hypothesis that hair graying as a visible marker of aging is associated with risk of coronary artery disease (CAD) independent of chronological age.MethodsThis cross-sectional study included 545 males who underwent a computed tomography coronary angiography (CTCA) for suspicious of CAD, patients were divided into subgroups according to the percentage of gray/white hairs (Hair Whitening Score, HWS: 1–5) and to the absence or presence of CAD.ResultsCAD was prevalent in 80% of our studied population, 255 (46.8%) had 3 vessels disease with mean age of 53.2 ± 10.7 yrs. Hypertension, diabetes and dyslipidemia were more prevalent in CAD group (P = 0.001, P = 0.001, and P = 0.003, respectively). Patients with CAD had statistically significant higher HWS (32.1% vs 60.1%, p < 0.001) and significant coronary artery calcification (<0.001). Multivariate regression analysis showed that age (odds ratio (OR): 2.40, 95% confidence interval (CI): [1.31–4.39], p = 0.004), HWS (OR: 1.31, 95% CI: [1.09–1.57], p = 0.004), hypertension (OR: 1.63, 95% CI: [1.03–2.58], p = 0.036), and dyslipidemia (OR: 1.61, 95% CI: [1.02–2.54], p = 0.038) were independent predictors of the presence of atherosclerotic CAD, and only age (p < 0.001) was significantly associated with HWS.ConclusionsHigher HWS was associated with increased coronary artery calcification and risk of CAD independent of chronological age and other established cardiovascular risk factors.

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“…Not only the age of the person, but also other factors such as genetics, nutrition, and metabolic and acquired disorders can change the hair structure and alter its optical properties . Furthermore, evidence suggests association between graying of hair and tobacco smoking and association of gray hair with facial wrinkling and fronto‐parietal baldness . On the other hand, research evidence indicates that the degree of graying of the hair is not predictive of shorter life span .…”

Section: Discussionmentioning

confidence: 99%

Age Estimation Based on Appearance of Gray Hair in Different Body Sites of Sri Lankan Autopsy Cases

Senanayake¹,

Wickramasinghe

2016

Journal of Forensic Sciences

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Owing to the scanty evidence on usefulness of information of appearance of gray hair for age estimation, this study was conducted to estimate age based on the appearance of gray hair on different body sites in a sample of autopsy cases in Sri Lanka. A descriptive cross-sectional study was conducted in Teaching Hospital-Kurunegala during 2011 to 2013. Based on the pattern of the presence of gray hair in different body sites, six stages of gray hair were computed. The analysis 1155 autopsy cases revealed strong, positive correlations between age and appearance of gray hair in head, mustache, beard, and pubic area among males and strong, positive correlations between age and the appearance of gray hair in head and pubic area among females (p < 0.01). Our findings demonstrate the value of information of appearance of gray hair for age estimation in the field of forensic science.

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Association between use of tobacco and age on graying of hair

Cited by 14 publications

References 11 publications

A review of the etiologies, clinical characteristics, and treatment of canities

A review of the etiologies, clinical characteristics, and treatment of canities

The degree of hair graying as an independent risk marker for coronary artery disease, a CT coronary angiography study

Age Estimation Based on Appearance of Gray Hair in Different Body Sites of Sri Lankan Autopsy Cases

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