Association Between Peak Expiratory Flow and the Development of Carotid Atherosclerotic Plaques

Abstract

Reduced lung function predicts the development of carotid atherosclerosis in elderly subjects. The nature of these associations remains largely unknown and merits further investigations. Nevertheless, assessment of lung function, which is simple and inexpensive, could help identify a population at high risk of atherosclerosis development and coronary heart disease.

Association between arterial stiffness and pulmonary function in hypertensive patients

“…Some previous studies [16][17][18][19] have demonstrated that airflow limitation with decreased predicted FEV 1 was associated with atherosclerosis. However, the atherosclerosis in the previous studies was assessed by carotid intima-media thickness and plaque.…”

“…11,12 Recent studies have demonstrated an association between COPD and cardiovascular disease, which accounts for approximately 25 to 50% of mortality. [13][14][15] Furthermore, recent studies [16][17][18][19] have demonstrated the association between pulmonary function and carotid atherosclerosis. These previous studies [16][17][18][19] assessed the atherosclerosis by measuring carotid intima-media thickness and plaques.…”

“…[13][14][15] Furthermore, recent studies [16][17][18][19] have demonstrated the association between pulmonary function and carotid atherosclerosis. These previous studies [16][17][18][19] assessed the atherosclerosis by measuring carotid intima-media thickness and plaques. Other previous studies 20,21 have demonstrated the association between pulmonary function and atherosclerosis by measuring arterial stiffness, which was assessed by aortic pulse wave velocity.…”

Sex-specific effect of body weight gain on systemic inflammation in subjects with COPD: results from the SAPALDIA cohort study 2

“…In fact, systemic inflammation may contribute to the diverse extrapulmonary comorbidities frequently seen in COPD patients, such as skeletal muscle wasting or cardiovascular disease [8,9], for which COPD is an independent risk factor [10]. Indeed, a leading cause of death in COPD includes cardiovascular disease, which is more frequent than respiratory failure in mild or moderate disease [11].…”

Guidelines for mechanical lung function measurements in psychophysiology

“…Despite a tight coupling of cardiac and pulmonary systems to meet the organism's metabolic demand, the latter system has been largely excluded from investigation under this perspective. Epidemiological studies have, however, uncovered the independent role of impaired mechanical lung function as a prognostic factor for the development of arteriosclerosis, myocardial infarction, stroke, and complications in diabetes~Ebi- Kryston, 1988;Klein, Moss, Klein, & Cruickshanks, 2001;Truelsen, Prescott, Lange, Schnohr, & Boysen, 2001;Zureik, Kauffmann, Touboul, Courbon, & Ducimetiere, 2001!. Considerable effort has been devoted to the standardization of lung function testing~American Association for Respiratory Care @AARC#, 1994American Thoracic Society @ATS#, 1991; British Thoracic Society and the Association of Respiratory Technicians and Physiologists, 1994; European Respiratory Society @ERS#, 1993, 1997!. Furthermore, textbooks are available on the basics of lung function testing in pulmonary medicine~e.g., Forster, DuBois, Briscoe, & Fisher, 1986;Stocks, Sly, Tepper, & Morgan, 1996!.…”