Association between Oral Health Status and Relative Handgrip Strength in 11,337 Korean

Kim, Jieun; Kim, Na-Yeong; Choi, Choong‐Ho; Chung, Ki‐Ho

doi:10.3390/jcm10225425

Cited by 5 publications

(4 citation statements)

References 30 publications

(45 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A recent cross-sectional study that include participants from the Korea National Health and Nutrition Examination Survey (KNHANES) database indicates that after adjustment for the risk factors of periodontitis, the likelihood of periodontitis decreased as the level of handgrip strength increased (OR = 0.986 [0.974, 0.999], p = 0.030) [26]. Ji-Eun Kim also revealed a signi cant association in the group of patients with periodontal disease (OR = 1.69 [1.51, 1.89]) [12]. In addition, it is the men in the youngest age group (30-49 years) showed the strongest association between PD and low hand grip strength [27].…”

Section: Discussionmentioning

confidence: 99%

“…The hand grip strength test is a simple and effective way of measuring muscle strength [9]. Considerable epidemiological evidence shows a signi cant association between PD and low handgrip strength [10][11][12]. However, there is no connection between hand grip strength and PD when adjusted for several variables [13].With inherent limitations of conventional observational studies, including small sample sizes and confounding and reverse causality, the causal relationship between PD and hand grip strength has yet to be established, which is extremely important and could improve our present understanding of PD and low hand grip strength pathogeneses.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Mendelian Randomization Rules Out Causation Between Periodontitis and Hand Grip Strength

Liu

et al. 2023

Preprint

View full text Add to dashboard Cite

Background: Periodontitis (PD) has been linked to low hand grip strength in previous epidemiological observational studies; however, the results are inconclusive. The purpose of this study was to investigate the causal association of PD with hand grip strength. Methods: We performed a two-sample bidirectional Mendelian randomization (MR) analysis using publicly released genome-wide association studies (GWAS) statistics. The inverse-variance weighted (IVW) method was used as the primary analysis. We applied three complementary methods, including weighted median, MR-Egger regression and MR pleiotropy residual sum and outlier (MR-PRESSO) to detect and correct for the effect of horizontal pleiotropy. Due to multiple testing, associations with p values < .016 were considered as statistically significant, and p values ≥ .016 and < .05 were considered as suggestively significant. Besides, a multivariable MR (MVMR) design was carried to adjust for body mass index (BMI) and type 2 diabetes (T2D) as well. Results: Generally, PD and one of subtypes-Aggressive Periodontitis (AgP) might not affect the risk of low hand grip strength (beta = 0.117 [-0.064, 0.298], beta = -0.018 [-0.042, 0.006]). However, genetically-elevated risk of Chronic Periodontitis (CP) might cause lower hand grip strength (beta = 0.035, p-value = 0.023) while turning insignificant at Bonferroni correction. Besides, no causal effect of hand grip strength on PD and CP was observed (OR = 0.987 [0.964, 1.009]). MVMR analysis also supported such null associations even after adjusting for BMI and T2D. Conclusion: This MR study ruled out the causal relationship between PD and hand grip strength, despite observational studies reporting an association between PD and hand grip strength.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Mendelian Randomization Rules Out Causation Between Periodontitis and Hand Grip Strength

Liu

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…However, in another study, it was reported that sarcopenia as a diagnostic criterion for handgrip strength and present teeth in participants aged over 80 years were related before adjusted [ 33 ]. Another study also reported an association between present teeth and low relative handgrip strength as continuous and categorical variables in adults [ 34 ]. This is in agreement with the results of our study, which suggests that oral health status, defined as having less than 20 teeth, may increase the risk of low muscle strength.…”

Section: Discussionmentioning

confidence: 99%

Association between Present Teeth and Muscle Strength in Older People in Korea

Kim

Choi

et al. 2022

JPM

Self Cite

View full text Add to dashboard Cite

Background: As the world population continues to age, interest in muscle strength loss in older people is increasing. This study aimed to confirm the association between present teeth and muscle strength in older people in Korea. Methods: Using data extracted from the 2014–2019 Korea National Health and Nutrition Examination Survey, we analyzed 5136 older people aged 65–79 years. The present teeth were based on 20 teeth, which is the criteria for comfortable mastication. The association of the risk of low muscle strength according to the present teeth was assessed using multiple logistic regression analysis, and the association was confirmed by dividing into subgroups according to sex. Results: The prevalence of low muscle strength was 17.87% among all participants. Multiple logistic regression analysis confirmed the association between low muscle strength and present teeth; a significant association was found even in the model in which all covariates were adjusted (odds ratios (OR) = 1.35; 95% confidence interval (CI): 1.13–1.61). Subgroup analysis revealed a significant association between present teeth and low muscle strength even in the model in which both covariates were adjusted for sex (Men, OR = 1.41; 95% CI: 1.02–1.95; Women, OR = 1.31; 95% CI: 1.06–1.6). Conclusion: An association between present teeth and low muscle strength was confirmed in older people in Korea. These results indicate that the importance of oral hygiene management should be emphasized to prevent muscle strength loss in older people.

show abstract

“…Hashimoto et al [ 37 ] suggested that older adults aged 80 years or above who showed high handgrip strength had more teeth than did those with low handgrip strength. In addition, cross-sectional studies among adults aged ≥19 years reported that people with low handgrip strength showed poorer oral health behaviors, including tooth brushing [ 38 , 39 ]. Therefore, considering previous studies and our findings, we infer that reduced handgrip strength has a direct and indirect adverse effect on the ability to perform daily oral care in adults aged ≥30 years and eventually contributes to developing periodontal inflammation over a prolonged period.…”

Section: Discussionmentioning

confidence: 99%

Association between Handgrip Strength and Periodontitis in Korean Adults Aged ≥30 Years: Data from the Korea National Health and Nutrition Examination Survey (2014–2015)

Choi

2022

IJERPH

View full text Add to dashboard Cite

This study used data from the Korea National Health and Nutrition Examination Survey 2014–2015 database to analyze the association between periodontitis and handgrip strength, a representative measure of hand impairment and function, in adults aged ≥30 years. The data of 5926 adults (male: 2766, females: 3160) who underwent handgrip strength and periodontal tissue examination and had neither rheumatoid arthritis nor osteoarthritis were analyzed. Handgrip strength was assessed using a digital grip strength dynamometer. The average values of the right handgrip strength, calculated separately by sex and age group (five 10-year age groups), were used as the cut-off for reduced handgrip strength. Periodontal status was evaluated using the Community Periodontal Index, defining scores ≥ 3 as periodontitis. Chi-square test and multivariate logistic regression analyses were performed to compare the differences in the prevalence of periodontitis according to handgrip strength. In the final regression model adjusted for risk factors for periodontitis, the likelihood of periodontitis decreased as the level of handgrip strength increased (p < 0.05). Therefore, this study suggests that handgrip strength may be a valuable indicator of periodontal health.

show abstract

Association between Oral Health Status and Relative Handgrip Strength in 11,337 Korean

Cited by 5 publications

References 30 publications

Mendelian Randomization Rules Out Causation Between Periodontitis and Hand Grip Strength

Mendelian Randomization Rules Out Causation Between Periodontitis and Hand Grip Strength

Association between Present Teeth and Muscle Strength in Older People in Korea

Association between Handgrip Strength and Periodontitis in Korean Adults Aged ≥30 Years: Data from the Korea National Health and Nutrition Examination Survey (2014–2015)

Contact Info

Product

Resources

About