Association Between Metabolic Syndrome and Radiographic Hand Osteoarthritis: Data From a Community‐Based Longitudinal Cohort Study

Abstract

We found no association between metabolic syndrome and hand OA. The role of hypertension in hand OA pathogenesis warrants further investigation.

Metabolic syndrome is not associated with erosive hand osteoarthritis: a cross-sectional study using data from the PROCOAC cohort

“…Additionally, a predictive model for EHOA incorporating MetS showed no modification in the results. This is in concordance with findings from the Strand publication based on the Framingham cohort, which found no significant association between hand OA, including EHOA, and MetS 44 . Notably, there was a borderline association with hypertension, aligning with our cohort data.…”

“…Our study adds to this complexity, emphasizing the need for further investigation. Notably, our analysis of EHOA patients did not demonstrate a significant association with MetS, consistent with findings from the Framingham cohort 44 .…”

Association of metabolic syndrome with knee and hand osteoarthritis: A community-based study of women

“…al. 40,42 did not find any association between MetS and hand ROA after adjusting for age, sex and BMI. Those findings are consistent with the present study for hand ROA without concurrent hand pain.…”

What Is the Evidence to Support the Association Between Metabolic Syndrome and Osteoarthritis? A Systematic Review

“…For hand OA, the only longitudinal study showed a null association . However, this study was of small sample size and studied only whites.…”

“…However, this study was of small sample size and studied only whites. We did not have sufficient data to reach a definitive conclusion in this review (Table ). The 2016 study by Tomi et al focused on patients with HIV and may not be generalizable to the general population .…”