Abstract:PURPOSE:To evaluate the effects of levobupivacaine on neuromuscular transmission and neuromuscular blockade produced by pancuronium in vitro.
METHODS:Thirty rats were distributed into groups (n = 5) according to the drug used alone or in combination: Group I -levobupivacaine (5 µg.mL-1 ); Group II -pancuronium (2 µg.mL -1 ); Group III -pancuronium (2 µg.mL -1 ) + levobupivacaine (5µg.mL -1 ). The following parameters were evaluated: 1) amplitude of diaphragmatic response to indirect stimulation, before and 60 … Show more
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