Association between dental health and obstructive coronary artery disease: an observational study

Abstract

Background The association between dental health and coronary artery disease (CAD) remains a topic of debate. This study aimed to investigate the association between dental health and obstructive CAD using multiple dental indices. Methods Eighty-eight patients (mean age: 65 years, 86% male) were prospectively enrolled before undergoing coronary CT angiography ( n = 52) or invasive coronary angiography ( n = 36). Obstructive CAD was defined as luminal stenosis of ≥50% for the left main coronary artery or ≥ 70% for the other epicardial coronary arteries. All patients underwent thorough dental examinations to evaluate 7 dental health indices, including the sum of decayed and filled teeth, the ratio of no restoration, the community periodontal index of treatment needs, clinical attachment loss, the total dental index, the panoramic topography index, and number of lost teeth. Results Forty patients (45.4%) had obstructive CAD. Among the 7 dental health indices, only the number of lost teeth was significantly associated with obstructive CAD, with patients who had obstructive CAD having significantly more lost teeth than patients without obstructive CAD (13.08 ± 10.4 vs. 5.44 ± 5.74, p < 0.001). The number of lost teeth was correlated with the number of obstructed coronary arteries ( p < 0.001). Multiple binary logistic regression analysis revealed that having ≥10 lost teeth was independently associated with the presence of obstructive CAD (odds ratio: 8.02, 95% confidence interval: 1.80–35.64; p = 0.006). Conclusions Tooth loss was associated with the presence of obstructive CAD in patients undergoing coronary evaluation. Larger longitudinal studies are needed to determine whether there is a causal relationship between tooth loss and CAD.

Relationship of periodontitis and edentulism to angiographically diagnosed coronary artery disease: A cross‐sectional study

“…Our findings also demonstrated that both edentulism and periodontitis are related to CAD and the edentulism could increase the odds ratio of CAD, like periodontitis. These results are consistent with studies showing an association between tooth loss and CAD 18,19,32,34,61‐63 . Zanella et al 18 found a significant interrelation between numerous tooth loss and vascular occlusion.…”

“…These results are consistent with studies showing an association between tooth loss and CAD. 18,19,32,34,[61][62][63] Zanella et al 18 found a significant interrelation between numerous tooth loss and vas- and they showed that CHD group had remarkably less teeth rather than the control group. In a meta-analysis study consisted of cohort studies, Bahekar et al 63 showed that subjects having less than 10 teeth exhibited 1.24 times more likely to develop CHD.…”

Determination of Infective Endocarditis Development Risks and Knowledge Levels of Individuals Applying for Dental Treatment

“…The form, which was created by the researchers by reviewing the literatüre [1][2][3][4][5], evaluating the sociodemographic characteristics of the individuals and their status related to dental treatment and cardiovascular disease (19 items) was used to collect data. The study also used a questionnaire to determine the presence of infective endocarditis signs and symptoms (11 items; yes, no; 2-point Likert type), the risk of developing infective endocarditis (20 items; yes, no; 2-point Likert type), and the level of knowledge of Oral Dental Health and Infective Endocarditis (17 items; strongly disagree, disagree, undecided, agree, strongly agree; 5-point likert type) created by the researchers in accordance with the literatüre [5][6][7][8][9][10]. The questionnaire used in the study consists of 67 items in total.…”

Enfermedad aterosclerótica intracraneal y pérdida dental severa en adultos mayores.

“…6,7 The association between tooth loss and atherosclerosis is found not only in the intracranial vasculature but in the coronary and peripheral vascular beds as well. [8][9][10] Moreover, biomarkers of systemic atherosclerosis -such as arterial stiffness -have also been associated with tooth loss. 11 This is not surprising, since atherosclerosis has long been considered an inflammatory disease.…”