Association Between Cardiovascular Risk Factors and 25(OH)D Levels in Obese Patients

Curvello-Silva, Karine Lima; Oliveira, Nataly Azenate Palhares de; Silva, Thalane S S; Sousa, Cláudia Daltro de; Daltro, Carla

doi:10.1089/met.2020.0023

Cited by 5 publications

(4 citation statements)

References 34 publications

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“…Additionally, all the three studies performed in the women with obesity [ 28 , 34 , 37 ] demonstrated that the significant inverse association between serum 25(OH)D and triglycerides was existed, while other lipid profiles including TC, LDL and HDL showed no statistical significance. Apart from the above two populations, the residual seven studies [ 20 , 21 , 30 , 32 , 39 , 41 , 42 ] indicating that serum 25(OH)D showed no clear correlation with any lipid profiles in the overweight/obesity population without diabetes complications.…”

Section: Resultsmentioning

confidence: 99%

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Association between vitamin D deficiency and lipid profiles in overweight and obese adults: a systematic review and meta-analysis

Huang,

Yang,

Jiang

et al. 2023

BMC Public Health

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Objective The association between vitamin D deficiency and lipid profiles in adults with overweight or obesity remains unclear and inconsistent. The aim of our study was to determine the relationship between lipid profiles and vitamin D deficiency in the overweight and obese adults. Methods Four databases, including PubMed, the Web of Science, EMBASE and the Cochrane Library, were used to identify all studies on vitamin D status and lipid levels, including the serum levels of triglycerides (TGs), total cholesterol (TC), low-density lipoprotein cholesterol (LDL), and high-density lipoprotein cholesterol (HDL). The Weighted mean difference (WMD) with 95% confidence intervals (CIs) using random-effects models was used to assess the association between the lipid profile and vitamin D deficiency. Results Twenty-one articles that included a total of 7952 adults with overweight or obesity (BMI ≥ 25 kg/m2) were included. The overall results revealed that compared with the controls, individuals with vitamin D deficiency showed higher levels of TG (WMD = 15.01; 95%CI, 2.51–27.52) and TC (WMD = 8.61; 95%CI, 1.31–15.92). Moreover, vitamin D deficiency was related to an increased level of LDL (WMD = 6.12; 95%CI, 0.02–12.23). HDL level was inversely associated with the vitamin D deficiency status (WMD = -2.57; 95%CI, -4.26, -0.88). Conclusions Among the adults with overweight or obesity, the vitamin D deficient group displayed impaired lipid profiles, including increased TG, TC and LDL levels and reduced HDL level.

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Section: Resultsmentioning

confidence: 99%

“…Apart from the above two populations, the residual seven studies [ 20 , 21 , 30 , 32 , 39 , 41 , 42 ] indicating that serum 25(OH)D showed no clear correlation with any lipid profiles in the overweight/obesity population without diabetes complications.…”

Section: Resultsmentioning

confidence: 99%

Association between vitamin D deficiency and lipid profiles in overweight and obese adults: a systematic review and meta-analysis

Huang,

Yang,

Jiang

et al. 2023

BMC Public Health

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“…In this context, the negative correlation noted between VDD and non-HDL in the current study is consistent with the results of some prior studies that assessed the atherogenic profile in obese females. 26,33,34 Furthermore, a negative association between the 25OHD level and the risk of CAD, including TG and LDL-C, has been suggested in healthy participants and patients. [33][34][35] In this respect, it has been demonstrated that people with normal serum 25OHD have a healthier lipid profile than those with VDD.…”

Section: Discussionmentioning

confidence: 99%

“…[22][23][24] In this context, lower 25-hydroxyvitamin D (25OHD) values were associated with lipid profile observations linked to atherogenic pathogenesis. 25,26 Although vitamin D 3 supplementation has been associated with a decreased risk of CVD in observational studies, 27,28 this association has not been verified in randomized clinical trials (RCTs). 19,29,30 For example, a recent large RCT with a total of 25,871 participants reported mixed evidence 31 and concluded that supplementation with vitamin D 3 did not result in a reduction in the incidence of invasive CVD in men and women aged 55 years or older.…”

Section: Introductionmentioning

confidence: 99%

The association of coffee consumption rate with serum 25-hydroxyvitamin D, non-HDL levels, and TC/HDL ratio in females with vitamin D deficiency

Habash¹,

Al-Shakhshir²,

Abusamak

et al. 2022

Womens Health (Lond Engl)

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Objectives: The purpose of this study was to evaluate the association of coffee consumption rate with serum 25-hydroxyvitamin D, non-high-density lipoprotein cholesterol levels, and total cholesterol to high-density lipoprotein cholesterol ratio in females with vitamin D deficiency. Methods: This retrospective cross-sectional study was carried out by studying the records of 270 Jordanian females aged 18–65 years with varying degrees of vitamin D deficiency. Following completion of the questionnaire regarding their anthropometric characteristics and coffee consumption rate during the preceding 3 months, the participants were required to provide blood samples for analysis to measure 25-hydroxyvitamin D and lipid profile levels including non-high-density lipoprotein cholesterol and total cholesterol to high-density lipoprotein cholesterol ratio. Results: The current study demonstrated that coffee consumption rate and vitamin D deficiency were significantly positively connected with the total cholesterol to high-density lipoprotein cholesterol ratio ( p = .003) in women with vitamin D deficiency. In addition, vitamin D deficiency alone correlated positively with non-high-density lipoprotein cholesterol levels and the total cholesterol to high-density lipoprotein cholesterol ratio ( p = .010) and ( p = .002), respectively. Conclusion: Higher coffee consumption rate among women with vitamin D deficiency significantly elevated total cholesterol to high-density lipoprotein cholesterol ratio that may increase woman’s risk of hyperlipidemia.

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Vitamin D3 deficiency and association with lipid metabolic disorders and body mass index

Jebur

2023

4th International Scientific Conference of Alkafeel University (Iscku 2022)

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Association Between Cardiovascular Risk Factors and 25(OH)D Levels in Obese Patients

Cited by 5 publications

References 34 publications

Association between vitamin D deficiency and lipid profiles in overweight and obese adults: a systematic review and meta-analysis

Association between vitamin D deficiency and lipid profiles in overweight and obese adults: a systematic review and meta-analysis

The association of coffee consumption rate with serum 25-hydroxyvitamin D, non-HDL levels, and TC/HDL ratio in females with vitamin D deficiency

Vitamin D3 deficiency and association with lipid metabolic disorders and body mass index

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