Assignment of six genes to bovine chromosome 13

Schläpfer, J.; Stahlberger-Saitbekova, Nasikhat; Womack, James E.; Gaillard, C.; Dolf, G.

doi:10.1046/j.1439-0388.2001.00285.x

Cited by 5 publications

(4 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The only polymorphism in the bovine open reading frame (ORF) so far detected is a difference in a number of repeats of the octa/nona-peptide Pro-His/Gln-Gly-(Gly)-Gly-Gly-Trp-Gly-Gln. PRNP alleles containing five, six or seven such elements are known 5,6 . The PRNP octarepeat allele genotype variations were analysed among the cattle in the USA, Belgium, Scotland and Switzerland [6][7][8][9][10] .…”

mentioning

confidence: 99%

See 1 more Smart Citation

PRNP octarepeat allele genotype frequencies among the modern and rare cattle breeds in Croatia

Premzl¹,

Bozic²,

Gamulin

2000

Animal Genetics

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 99%

“…PRNP alleles containing five, six or seven such elements are known 5,6 . The PRNP octarepeat allele genotype variations were analysed among the cattle in the USA, Belgium, Scotland and Switzerland [6][7][8][9][10] . No major differences were detected among various modern cattle breeds with an exception of Swiss Brown breed in Switzerland 6 .…”

mentioning

confidence: 99%

PRNP octarepeat allele genotype frequencies among the modern and rare cattle breeds in Croatia

Premzl¹,

Bozic²,

Gamulin

2000

Animal Genetics

View full text Add to dashboard Cite

show abstract

“…A sequence database search (BLASTN) [1], using the EST BE217249 and AF213840/H12715 as query sequences identified human DNA sequences (EMBL accession number AL161799 and AL390294) from clones assigned to HSA 10 as the most likely homologues (data not shown). Considering that the genes which were included in this present map are relatively evenly distributed over both arms of HSA20, and the fact, that the ordering of six newly assigned genes on BTA13 [21] has not identified the postulated HSA20 homologous segment, might point towards a reevaluation of the ZOO-FISH findings. However, the postulated HSA20 homologous segment located close to the centromere on BTA13, could represent an evolutionarily conserved block of non-coding DNA.…”

Section: Discussionmentioning

confidence: 94%

A higher resolution radiation hybrid map of bovine chromosome 13

Schläpfer¹,

Stahlberger-Saitbekova

Comincini

et al. 2002

Genet. Sel. Evol.

View full text Add to dashboard Cite

-In this paper, we present a radiation hybrid framework map of BTA13 composed of nine microsatellite loci, six genes and one EST. The map has been developed using a recently constructed 12 000 rad bovine-hamster whole-genome radiation hybrid panel. Moreover, we present a comprehensive map of BTA13 comprising 72 loci, of which 45 are microsatellites, 20 are genes and seven are ESTs. The map has an estimated length of 2694.7 cR 12 000 . The proposed order is in general agreement with published maps of BTA13. Our results only partially support previously published information of five blocks of conserved gene order between cattle and man. We found no evidence for the existence of an HSA20 homologous segment of coding DNA on BTA13 located centromeric of a confirmed HSA10 homologous region. The present map increases the marker density and the marker resolution on BTA13 and enables further insight into the evolutionary development of the chromosome as compared to man. bovine chromosome 13 / radiation hybrid / gene mapping / 12 000 rad / comparative mapping * Correspondence and reprints

show abstract

“…Brindle was described as alternating stripes of red and black hair pigmentation. Agouti signaling protein was assigned to BTA13 through somatic cell hybrid analysis by Schlӓpfer et al (2001).…”

Section: Genomic Regions Known To Influence Cattle Coat Colormentioning

confidence: 99%

009 Identification of regions of the bovine genome associated with gray coat color in a Nellore_Angus cross population

Holland

Gill

Herring

et al. 2016

Journal of Animal Science

View full text Add to dashboard Cite

The genetics of coat color for cattle are important to breeders and breed associations because phenotypes of these animals are used for breed recognition and premiums or discounts can be given due to the phenotypes. The gene for gray coat color has been determined in other species, but not in cattle. Gray in cattle is known to be recessive based upon observed inheritance. The objective of this study was to identify the regions of the bovine genome associated with gray coat color in a population of Nellore-Angus crossbred cattle. Additionally, proportions of each color and spotting were of interest.Animals (n = 1941) were classified into phenotypic color categories (i.e. red, black, gray, etc.). Proportions of each color group out of the population were determined, and the proportion of those phenotypes that have any form of spotting. Two genome-wide association analyses were conducted, one where phenotypically gray vs. not gray cattle were analyzed and another where cattle that were very light in color but had a reddish tinge were included as gray. Analyses used Bonferroni correction at α = 0.05 (α/ntests = 1.49 × 10 -6 ). Analysis of gray vs. not gray yielded one significant SNP marker on BTA6 at a location of 68,059,441 bp (Praw = 9.69 × 10 -7 , Padjusted = 0.032) (UMD_3.1, NCBI project 32899, Gen Bank GCA_000003055.3). For the analysis of gray and reddish tinged vs. not gray, there were 5 significant markers all on BTA6 forming a region from 62.93 Mb to 83.92 Mb (UMD_3.1, NCBI project 32899, Gen Bank GCA_000003055.3).The same SNP marker from the first analysis was present in iii the second, but had an increased significance (Praw = 1.50 × 10 -10 , Padjusted = 5.02 × 10 -6 ).The region on BTA6 ruled out syntaxin-17 (STX17) on BTA8 and premelanosome protein (PMEL) on BTA5, previous gray candidate genes from other species, but includes genes such as v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT), which is known to cause white coloration (spotting), and platelet-derived growth factor receptor alpha polypeptide (PDGFRA), the strongest candidate gene for the reddening in Nellore-Angus cattle, and corin serin pepsidase (CORIN), known for lighter coloration.iv DEDICATION This thesis is dedicated to the memory of my father, Mike Holland. I miss him every day. He was the hardest working man I know, who did everything for the sake of his family. Without him I would not have had the opportunities in life that I have had and I thank him for that. He always supported me in my choices and was always asking me about school. He was always on my mind while working on this research and the examples he set for me as a person kept me working and prevented me from giving up. v ACKNOWLEDGMENTS

show abstract

Assignment of six genes to bovine chromosome 13

Cited by 5 publications

References 28 publications

PRNP octarepeat allele genotype frequencies among the modern and rare cattle breeds in Croatia

PRNP octarepeat allele genotype frequencies among the modern and rare cattle breeds in Croatia

A higher resolution radiation hybrid map of bovine chromosome 13

009 Identification of regions of the bovine genome associated with gray coat color in a Nellore_Angus cross population

Contact Info

Product

Resources

About