Assessment of the Scopa-Aut questionnaire in multiple system atrophy: Relation to UMSARS scores and progression over time

Damon-Perrière, Nathalie; Foubert‐Samier, Alexandra; Cock, Valérie Cochen De; Gerdelat-Mas, A.; Debs, Rachel; Traon, Anne Pavy-Le; Senard, Jean‐Michel; Rascol, Olivier; Tison, François; Meissner, Wassilios G.

doi:10.1016/j.parkreldis.2011.12.009

Cited by 25 publications

(15 citation statements)

References 10 publications

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“…It is not known whether the trend for a longer life span in patients with MSA-P would reach significance with a larger number of subjects, but in a recent study (Wenning et al 2013) MSA-P was associated with shorter rather than longer survival. We found that SCOPA-AUT scores correlated with UMSARS-I (which measure functional disability) but not with UMSARS-II scores (which measure motor disability), similarly to a recent report (Damon-Perriere et al 2012). …”

Section: Discussionsupporting

confidence: 91%

Cerebellar and parkinsonian phenotypes in multiple system atrophy: similarities, differences and survival

et al. 2013

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Multiple system atrophy (MSA) is a neurodegenerative disease with two motor phenotypes: parkinsonian (MSA-P) and cerebellar (MSA-C). To elucidate whether in addition to the motor abnormalities there are other significant differences between these phenotypes we performed a retrospective review of 100 patients (61 males, 39 females) with a diagnosis of possible (12%), or probable (88%). Four patients eventually had postmortem confirmation (i.e., definite MSA). Sixty percent were classified as having MSAP and 40% as MSA-C. MSA-C and MSA-P patients had similar male prevalence (60%), age of onset (56±9 years), and frequency of OH (69%). Brain MRI abnormalities were more frequent in MSA-C patients (p<0.001). Mean survival was 8±3 years for MSA-C and 9±4 years for MSA-P patients (p=0.22). Disease onset before 55 years predicted longer survival in both phenotypes. Initial autonomic involvement did not influence survival. We conclude that patients with both motor phenotypes have mostly similar survivals and demographic distributions. The differences here identified could help counseling of patients with MSA.

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Section: Discussionsupporting

confidence: 91%

Cerebellar and parkinsonian phenotypes in multiple system atrophy: similarities, differences and survival

et al. 2013

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“…This tendency was compatible with previous reports. In this study, there were 0.4-0.8% missing answers, and there were 5.9-6.6% invalid answers for all of the items, which was similar to a previous study (0.8-1.0%) [3]. Invalid answers accounted for more than two-thirds of the questions about sexual dysfunction.…”

Section: Discussionsupporting

confidence: 88%

“…The earlier study on the use of the SCOPA-AUT in patients with MSA [3] was more heterogeneous than those studies that included only patients with PD. Thus, the SCOPA-AUT may be suitable for screening nonhomogeneous diseases, such as MSA.…”

Section: Discussionmentioning

confidence: 98%

“…The English and Portuguese versions of the SCOPA-AUT have been validated [2], but the Japanese version of the SCOPA-AUT has not been published nor tested for its reliability. The SCOPA-AUT can be applied to patients with various neurological disorders because it has recently been used to assess non-PD patients, such as those with multiple system atrophy (MSA) and Huntington's disease [3] [4]. Thus, we prepared the Japanese version of the SCOPA-AUT.…”

Section: Introductionmentioning

confidence: 99%

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Reliability of the Japanese version of the scales for outcomes in Parkinson's disease-autonomic questionnaire

Matsushima

Yabe

Hirotani

et al. 2014

Clinical Neurology and Neurosurgery

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Methods: We translated the SCOPA-AUT from English to Japanese. Thirty-one patients with diseases involving autonomic symptoms completed the form twice. The reliability was assessed by Cronbach's coefficient alphas and intraclass correlation coefficients (ICCs).Results: The average (standard deviation, SD) total scores of the first and second assessments of the SCOPA-AUT were 15.7 (SD, 7.1) and 13.6 (SD, 6.5), respectively. The Cronbach's coefficient alphas were globally high, but the ICCs were moderately high. The valid response rates for the questions about sexual dysfunction were 36.7% in men and 26.6% in women.Conclusions: The Japanese version of the SCOPA-AUT had high internal consistency. However, the questions about sexual dysfunction showed less valid response rates.

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“…While one report used this scale for MSA evaluation [28], it was originally developed for Parkinson's disease. However, typically, the SCOPA-AUT does not adequately assess motor function.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Different Symptom Assessment Scales for Multiple System Atrophy

et al. 2015

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Sixty-nine patients were examined after 6 months and 63 patients after 12 months. The UMSARS Part 4 had the largest SRM after 6 months and the SARA after 12 months. SRMs for MSA-P, the shorter duration group, and the early-onset group were larger than were those for MSA-C, the longer duration group, and the late-onset group. SRMs for items regarding skilled hand activities, walking, and standing were relatively large. Our study indicates that the UMSARS (parts 2 and 4), SARA, and BBS are sensitive scales for evaluating MSA progression over 12 months. Items with large SRMs effectively evaluated short-term changes.

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Assessment of the Scopa-Aut questionnaire in multiple system atrophy: Relation to UMSARS scores and progression over time

Cited by 25 publications

References 10 publications

Cerebellar and parkinsonian phenotypes in multiple system atrophy: similarities, differences and survival

Cerebellar and parkinsonian phenotypes in multiple system atrophy: similarities, differences and survival

Reliability of the Japanese version of the scales for outcomes in Parkinson's disease-autonomic questionnaire

Comparison of Different Symptom Assessment Scales for Multiple System Atrophy

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