Assessment of Selenium in Roux-en-Y Gastric Bypass and Gastric Banding Surgery

Abstract

This study shows that RNY gastric bypass and laparoscopic adjustable gastric banding procedures, and accompanying dietary restrictions, increases the risk for disturbances of selenium and GTP homeostasis. Consideration for selenium supplementation at higher levels than the current RDA of 55 mcg daily during the first 3 months and perhaps longer should be studied further.

Copper, selenium and zinc levels after bariatric surgery in patients recommended to take multivitamin-mineral supplementation

“…Similar findings for selenium levels after bariatric surgery, with early postoperative decrease and subsequent normalization have also been reported in previous studies [16]. However, another study has reported decreased selenium levels long-term after bariatric surgery compared to matched controls who did not receive bariatric operation [27].…”

“…Severe selenium deficiency can cause symptoms and diseases including myopathy, cardiomyopathy, arrhythmia, muscle wasting, impaired immunity, low thyroid function, loss of skin and hair pigmentation, whitened nail beds, and progressive encephalopathy [15,16]. On the other hand, zinc deficiency has been reported to cause diarrhoea, emotional disorders, weight loss, intercurrent infection, bullous-pustular dermatitis, and hypogonadism in males [15,17].…”

Risk of Malnutrition, Trace Metal, and Vitamin Deficiency Post Roux-en-Y Gastric Bypass—a Prospective Study of 20 Patients with BMI <35 kg/m2

“…We also found a decrease in selenium serum concentrations and selenium deficiency in 46 % of patients, as well as a drop in zinc serum concentrations and zinc deficiency in 15 % of patients. These values are in line with previously published selenium and zinc deficiency rates after RYGB for obese patients [22][23][24][25]. The decrease can be explained by the bypassing of the selenium resorption site in the duodenum and proximal jejunum [26].…”

Dermatological Complications after Bariatric Surgery: Report of Two Cases and Review of the Literature

“…Recommendations for prophylactic vitamin and trace element supplementation include oral or sublingual administration of 1 mg of B 12 daily or intramuscular administration of 1 mg of B 12 monthly, 800 μg to 1 mg of folic acid daily, up to 60 mg of oral zinc daily, 36-65 mg of elemental iron daily, at least 3,500 IU of vitamin A daily, 2,000 IU of vitamin D 3 along with 1,500 mg of calcium daily and vitamin D 2 at a dose of 50,000 IU weekly [11] and at least 55 μg of selenium daily [12]. Occasionally, skin lesions are the first indication of vitamin or trace element deficiency and should trigger further research from a dermatological perspective.…”

“…This may become more prominent 3 months after surgery on average, thus selenium supplementation during this time period seems reasonable [27]. Selenium deficiency has been associated with skin dryness, erythematous scaly plaques, cheilitis and light-colored hair [15].…”