Assessment of repolarization heterogeneity for prediction of mortality in cardiovascular disease: peak to the end of the T wave interval and nondipolar repolarization components

Smetana, Peter; Schmidt, Anna; Zabel, Markus; Hnatkova, Katerina; Franz, Michael R.; Huber, Kurt; Malik, Marek

doi:10.1016/j.jelectrocard.2011.03.004

Cited by 146 publications

(110 citation statements)

References 42 publications

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“…TPE interval and TPE/QT ratio have been used as new ECG markers of increased dispersion of ventricular repolarization. Prolongation of the TPE interval has been identified to be related with ventricular arrhythmia and sudden cardiac death [26][27][28][29][30]. Electrophysiological studies have shown that TPE interval prolongation is associated with ventricular tachycardia induction and the spontaneous occurrence of ventricular tachycardia [21,22].…”

Section: Resultsmentioning

confidence: 99%

Ventricular Repolarization Intervals in Children Previously Treated with Anthracyclines

2017

ARC Journal of Cardiology

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Section: Resultsmentioning

confidence: 99%

Ventricular Repolarization Intervals in Children Previously Treated with Anthracyclines

2017

ARC Journal of Cardiology

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“…It has been shown that the QT interval lengthened and QTd increased after sympathetic system activity or catecholamine discharge [28]. The Tp-e interval and Tp-e/QT ratio have been used as indices of ventricular repolarization to predict ventricular arrhythmias and sudden cardiac death [13][14][15][16][17]. Several investigators have studied repolarization patterns in patients with SCF and have shown that QTd, Tp-e interval and Tp-e/QT ratio were increased compared to controls [11,29].…”

Section: Discussionmentioning

confidence: 99%

“…The Tp-e interval, defined as the duration between the peak and the end of the T wave on a surface ECG, is an indicator of the total dispersion of repolarization [13]. In addition, Tp-e might be a predictor of ventricular tachycardias and cardiovascular mortality [14,15]. However, changes in body weight and heart rate affect the Tp-e interval [16].…”

Section: The Relationship Between Ventricular Repolarization Indexes mentioning

confidence: 99%

The Relationship between Ventricular Repolarization Indexes and Neutrophil to Lymphocyte Ratio in Patients with Slow Coronary Flow

Suner¹,

Yaşar²

2016

Ann Clin Lab Res

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“…Recent studies indicated that Tp-e interval, which is the interval between the peak and the end of T wave on electrocardiogram (ECG), can be used as an index of total (transmural, apicobasal, and global) dispersion of repolarization [24,25]. Also, increased Tp-e interval might be a useful index to predict ventricular tachyarrhythmias and cardiovascular mortality [9]. Recently, a new index, the Tp-e/QT ratio has been suggested to be a more accurate measure of the dispersion of ventricular repolarization compared to QTd, cQTd, and Tp-e intervals which are independent of alterations in heart rate [10].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Tp-e interval and Tp-e/ QTc ratio in patients with mild to moderate psoriasis

Ozluk¹,

Yılmaz²,

Topal³

et al. 2016

Eur Res J

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Objectives. Many systemic diseases including cardiovascular disturbances have been described in psoriatic patients. In the previous studies, left ventricle (LV) subclinical myocardial dysfunction was reported in the psoriasis patients. The T-wave peak to end (Tp-e) interval is a relatively new marker for ventricular arrhythmogenesis and repolarization heterogeneity. Prolongation of this interval represents a period of potential vulnerability to ventricular arrhythmias. However, there is no information available assessing the Tp-e interval and related calculations in patients with psoriasis disease. The aim of this study was to evaluate ventricular repolarization in patients with psoriasis disease by using QT, corrected QT (QTc) and Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio. Methods. In this study, retrospective analysis of 30 patients who underwent the psoriasis treatment and of 30 healthy individuals was performed. The severity of the disease was evaluated by the "Psoriasis Area and Severity Index". QT, corrected QT (QTc), Tp-e interval and Tp-e/QT ratio were measured by means of the 12-lead electrocardiogram. Left ventricular function was evaluated by echocardiography. Results. Baseline characteristics and QT and QTc intervals were similar in both groups. No difference was detected between the groups with regards to Tp-e interval (83.0±9 vs 82.3±10; p=0.81), Tpe/QT (0.22±0.03 vs 0.23±0.04; p=0.3) and p=0.77). Conclusions. These findings suggest that ventricular repolarization in mild to moderate psoriasis patients might be unimpaired. Larger samples and severe degree psoriasis patients are needed to evaluate the arrhythmia risk in psoriasis patients.Eur Res J 2016;2(1):46-51

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Assessment of repolarization heterogeneity for prediction of mortality in cardiovascular disease: peak to the end of the T wave interval and nondipolar repolarization components

Cited by 146 publications

References 42 publications

Ventricular Repolarization Intervals in Children Previously Treated with Anthracyclines

Ventricular Repolarization Intervals in Children Previously Treated with Anthracyclines

The Relationship between Ventricular Repolarization Indexes and Neutrophil to Lymphocyte Ratio in Patients with Slow Coronary Flow

Evaluation of Tp-e interval and Tp-e/ QTc ratio in patients with mild to moderate psoriasis

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