2008
DOI: 10.1590/s0100-736x2008000200001 View full text |Buy / Rent full text
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Abstract: The relation between hyperglycemia and diabetic neuropathy has already been demonstrated in some studies. Among the theories proposed for its etiology the oxidative stress stands out. The performance of nitric oxide as a link between the metabolic and vascular neuropathogenic factors that triggers the diabetic neuropathy has already been put forward. This study aimed to assess the quantification and measurements of the cell body profile area (CBPA) of NADPH-diaphorase reactive (NADPH-dp) myenteric neurons of t… Show more

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“…The PC areas in Group DS and CS were 12.7% and 27.5% lower when compared to Group D and C, respectively (Table 2). A similar effect of the AA treatment on the PC area of diabetic animals is reported in the jejunum (Silverio et al 2008) and in the ileum of rats that remained diabetic for 120 days (Zanoni et al 2003).…”
Section: Discussionsupporting
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“…The PC areas in Group DS and CS were 12.7% and 27.5% lower when compared to Group D and C, respectively (Table 2). A similar effect of the AA treatment on the PC area of diabetic animals is reported in the jejunum (Silverio et al 2008) and in the ileum of rats that remained diabetic for 120 days (Zanoni et al 2003).…”
Section: Discussionsupporting
“…Zanoni et al (2003) and Silverio et al (2008) have also found a decreased frequency of neurons in the PC area exceeding 200ìm 2 and an increased incidence of neurons with a PC area lower less than to 200ìm 2 in the ileum and jejunum of myenteric plexus of STZ-induced diabetic rats AA-treated, although with not with the same percentage.…”
Section: Discussionmentioning
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