Abstract:Free light chains (FLC), considered a biomarker of B cell activity, are
frequently elevated in different systemic inflammatory-autoimmune
diseases. As systemic sclerosis (SSc) clinical course may be variable,
this study aimed to assess FLCs levels in serum and urine of affected
individuals, as biomarkers of disease activity. We assessed FLC levels
in serum and urine of 72 SSc patients and 30 healthy controls (HC).
Results were analyzed in comparison with overall clinical and laboratory
findings, disease activi… Show more
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