Assessment of glycemic potential ofMusa paradisiaca stem juice

Abstract

The present study reveals the effect of Musa paradisiaca stem juice on blood glucose level (BGL) Address for Correspondence :Dr. Geeta Watal Alternative Therapeutics Unit, Drug Development Division, Medicinal Research Lab, Department of Chemistry, University of Allahabad, Allahabad -211002 E-mail : geetawatal@gmail.com banana fruit pulp to treat ulcers have been explored by a number of investigators (9-12). Since, the flowers and the roots of Musa sapientum showed hypoglycemic effect on normal fasting rabbits (13-14) and the chloroform extract of its flowers showed a reduction in blood glucose, glycosylated hemoglobin and an increase in total haemoglobin (15-16). Therefore the present investigation was under taken to evaluate the effect of M. paradisiaca stem juice on blood glucose level (BGL) of normal and streptozotocin induced diabetic rats in order to assess its glycemic potential. MATERIALS AND METHODS Chemicals :Streptozotocin was purchased from SigmaAldrich Co. USA. BGL (blood glucose level) for FBG (fasting blood glucose) and GTT (glucose tolerance test) studies were assayed using Kits from Bayer Diagnostics, India. One touch (Accu-chek sensor) of Roche Diagnostics, Germany. Solvents from E.Merk. Animals :Male albino wistar rats of body weight about 170-220 gm were used in the experiments. Animals were kept in animal house at an ambient temperature of 25 -30°C and 45-55% relative humidity with a 12h each of dark and light cycle. Animals were fed pellet diet (Golden feed, New Delhi) and water ad-libitum. For experimental purpose the animals were kept fasting overnight but were allowed to free access to water "Principles of laboratory animals care" (NH publication no. 85-23, revised 1985) were followed.

Beneficial effects of low dose Musa paradisiaca on the semen quality of male Wistar rats

“…The precise mechanism of action by which MEMP does this is still unclear. Musa paradisiaca has hypoglycaemic effects in both normal and diabetic animal models, and this might be a reason for its ability to facilitate improvement in male sexual functions in diabetic animals 10202324. This is true when the mature green fruit of plantain is consumed at a moderate dose, as revealed in the current study, where consumption of Musa paradisiaca at a low dose led to improvement in the quantity and quality of spermatozoa in adult Wistar rats.…”

Banana by-products: an under-utilized renewable food biomass with great potential

“…Dwarf Cavendish) indicate its potential application as a source of functional food products (Oliveira et al 2008). A separate study done by Singh et al (2007) revealed that oral administration of banana pseudostem juice (Musa paradisiaca) to the normal and hyperdiabetic (high glucose level in blood) rats shows a significant increase of blood glucose level, signify a possible treatment hypoglycemic patients due to low insulin level or hypoglycemic drugs.…”

Antihyperglycemic Activity of Banana (Musa nana Lour.) Peel and Its Active Ingredients in Alloxan-Induced Diabetic Mice

“…elakki bale banana flower [15], M. sapientum Linn. stem juice [16], Musa paradisiacal stem juice [17], Musa sp. var.…”