Assessment of efficacy and tolerability of different concentrations of trichloroacetic acid <i>vs</i>. carbon dioxide laser in treatment of xanthelasma palpebrarum

Mourad, Basma; Elgarhy, Lamia Hamouda; Ellakkawy, Heba-Alla; El-Mahdy, Nageh Ahmed

doi:10.1111/jocd.12148

Cited by 29 publications

(42 citation statements)

References 22 publications

(37 reference statements)

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“…A total of nine studies were included that utilized the CO 2 laser to treat patients with xanthelasma palpebrarum . Study findings are summarized in Table .…”

Section: Resultsmentioning

confidence: 99%

“…TCA application is simple and straightforward but can cause scar formation and ectropion . When compared to TCA, laser therapy requires fewer sessions and less downtime, also producing better cure rates and fewer recurrences . While cryosurgery has relatively minimal side effects, its use can be complicated by high recurrence rates and secondary infection .…”

Section: Introductionmentioning

confidence: 99%

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Systematic review of laser therapy in xanthelasma palpebrarum

2017

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Xanthelasma palpebrarum is a benign periorbital xanthoma with substantial cosmetic and psychosocial burden for patients. Treatment modalities should be considered based on efficacy as well as cosmetic outcome. Laser modalities in the treatment of xanthelasma palpebrarum have not been comprehensively reviewed and discussed. Accordingly, this study seeks to systematically and critically review the available literature discussing laser treatment of xanthelasma palpebrarum. PubMed was systematically reviewed for reports on laser therapy in the treatment of xanthelasma palpebrarum. A total of 21 studies were included in this review discussing laser treatment of xanthelasma palpebrarum. Laser types included carbon dioxide, yttrium aluminum garnet, pulsed dye, argon, and a 1450 nm diode laser. The carbon dioxide laser was the most commonly reported modality followed by yttrium aluminum garnet laser. All of the laser modalities offered moderate to excellent clearance rates with minimal side effect profiles. Further large scale studies comparing different laser modalities are required to determine the best laser modality. However, laser modalities as a whole offer a treatment option for xanthelasma palpebrarum, that is, cosmetically excellent with a reasonable side-effect profile.

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“…A total of nine studies were included that utilized the CO 2 laser to treat patients with xanthelasma palpebrarum . Study findings are summarized in Table .…”

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Systematic review of laser therapy in xanthelasma palpebrarum

2017

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“…Xanthelasmas start in the reticular dermis or subdermis and progress to the subcutaneous layer and orbicularis oculi muscle. Various treatment options are available including excision, 4,5 trichloroacetic acid (TCA) peeling, 6,7 cryotherapy, argon laser, 8 CO2 laser, 9,10 and Nd:YAG laser therapy. 11,12 Small lesions can be effectively treated by surgical excision.…”

Section: Discussionmentioning

confidence: 99%

“…Various treatment options for xanthelasma palpebrarum are available, including surgical excision, 4,5 chemical peeling, 6,7 cryotherapy, argon laser, 8 carbon dioxide (CO2) laser, 9,10 and neodymium:yttrium aluminum garnet (Nd:YAG) laser. 11,12 However, the results thereof are generally suboptimal and involve high recurrence rates.…”

Section: Introductionmentioning

confidence: 99%

Erbium:Yttrium Aluminum Garnet Laser Treatment for Xanthelasma Palpebrarum

et al. 2017

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Xanthelasma palpebrarum is presented as a yellow plaque on the eyelids. Xanthelasma lesions are composed of fat cells that accumulate in the dermis and subcutaneous layer; progressive accumulation involves the orbicularis oculi muscle. Most patients with this condition request to have the lesion removed for cosmetic reasons, for which various treatment options are available, including surgical excision, chemical peeling, cryotherapy, argon laser, carbon dioxide (CO 2 ) laser, and neodymium:yttrium aluminum garnet (Nd:YAG) laser. Nevertheless, xanthelasmas are difficult to remove completely and has a high chance of recurrence. Recently, we were able to completely remove xanthelasma palpebrarum lesions in nine patients using erbium (Er):YAG laser. The Er:YAG laser seemed to maximize ablation effects, allowing us to easily determine whether the lesion had been completely removed. Moreover, we noted that, due to minor residual thermal damage, wound healing occurred rapidly with minimum side effects. Key words

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“…Many treatments are available for management of XP, the most commonly used include surgical excision, ablative CO 2 or erbium lasers, nonablative Q‐switched Nd:YAG laser, trichloroacetic acid peeling, and radiofrequency (RF) ablation …”

Section: Introductionmentioning

confidence: 99%

Long‐wave plasma radiofrequency ablation for treatment of xanthelasma palpebrarum

Baroni

2018

J of Cosmetic Dermatology

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Xanthelasma palpebrarum is the most common type of xanthoma affecting the eyelids. It is characterized by asymptomatic soft yellowish macules, papules, or plaques over the upper and lower eyelids. Many treatments are available for management of xanthelasma palpebrarum, the most commonly used include surgical excision, ablative CO or erbium lasers, nonablative Q-switched Nd:YAG laser, trichloroacetic acid peeling, and radiofrequency ablation. This study aims to evaluate the effectiveness of RF ablation in the treatment of xanthelasma palpebrarum, with D.A.S. Medical portable device (Technolux, Italia), a radiofrequency tool working with long-wave plasma energy and without anesthesia. Twenty patients, 15 female and 5 male, affected by xanthelasma palpebrarum, were enrolled for long-wave plasma radiofrequency ablation treatment. The treatment consisted of 3/4 sessions that were carried out at intervals of 30 days. Treatments were well tolerated by all patients with no adverse effects and optimal aesthetic results. The procedure is very fast and can be performed without anesthesia because of the low and tolerable pain stimulation. Long-wave plasma radiofrequency ablation is an effective option for treatment of xanthelasma palpebrarum and adds an additional tool to the increasing list of medical devices for aesthetic treatments.

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Assessment of efficacy and tolerability of different concentrations of trichloroacetic acid vs. carbon dioxide laser in treatment of xanthelasma palpebrarum

Abstract: Both TCA peeling 70% and carbon dioxide laser ablation are highly effective and well tolerated with least number of sessions in the treatment of xanthelasma palpebrarum.

Cited by 29 publications

References 22 publications

Systematic review of laser therapy in xanthelasma palpebrarum

Systematic review of laser therapy in xanthelasma palpebrarum

Erbium:Yttrium Aluminum Garnet Laser Treatment for Xanthelasma Palpebrarum

Long‐wave plasma radiofrequency ablation for treatment of xanthelasma palpebrarum

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