Assessment of directly observed therapy short-course (DOTs) of tuberculosis in Dakahlia governorate chest hospitals from 2006 to 2011

Negm, Medhat F.; Allam, Amira H.; Zeheiry, Fatehia S. El

doi:10.4103/ejb.ejb_55_16

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…There is a difference in the distribution of TB between governorate studies where El-Behira [6], Dakahlia [14], Qalyobia, Minofia, Assiut [1], Sohag [15], and Aswan [3] showed that TB cases were more in rural areas. Those studies explained that higher TB cases in rural areas owing to poverty, drinking contaminated milk, exposure to cough spray from infected cattle, or close physical contact with infected animals.…”

Section: Discussionmentioning

confidence: 99%

Retrospective study of pulmonary and extrapulmonary tuberculosis cases in Giza Governorate during the period of 2014–2018

Malik¹,

Wahab

Eltrawy

2021

Egypt J Bronchol

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Background Tuberculosis in Egypt is a main public health problem. Egypt is categorized among the mid-level incidence countries. The objective of this work is to study the epidemiology of TB in Giza Governorate during the period from 2014 to 2018. Results This study revealed that the total number of TB cases in Giza Governorate during the period from 2014 to 2018 was 3357 (2035 males and 1322 females including 199 children) with the highest number of cases in 2017 (n=770 cases). The highest incidence occurred in the age group 18–65 years (86.3%%, 78.8%, 83.8%, 84.2%, and 87.1%) and male gender (56.8%, 62.8%, 59.9%, 61.3%, and 61.5%) during the study period, respectively, and in urban residence, the higher percentage occurred in PTB than EPTB in 2014, 2015, 2016, and 2018 (66.2%, 58.9%, 57.3%, and 55.5%), respectively, while the incidence of the extra PTB was higher than PTB in 2017 (51.6% versus 48.4%). The increased incidence of new cases (92.9%, 89.6%, 92.7%, 91.8%, and 92.9%) during the 5 studied years are smear-positive and cure outcome (86.3%, 87.7%, 88.7%, 83.4%, and 83.4%, respectively) Conclusion Young, middle-aged male, and new smear-positive cases were highest in percentage. The highest percentage of PTB (66.2%) was registered in 2014, and the highest percentage of EPTB (51.6%) was registered in 2017. The increased percentage of cure outcome was during the period from 2014 to 2018 in Giza Governorate.

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Section: Discussionmentioning

confidence: 99%

Retrospective study of pulmonary and extrapulmonary tuberculosis cases in Giza Governorate during the period of 2014–2018

Malik¹,

Wahab

Eltrawy

2021

Egypt J Bronchol

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Tuberculosis situation in Ismailia governorate (2002–2012) before and after Direct Observed Therapy Short Course Strategy (DOTS)

Negm

mehy

Ali

et al. 2016

Egyptian Journal of Chest Diseases and Tuberculosis

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Sociodemographic, microbial and phylogentic studies of Mycobacterium tuberculosis cases diagnosed in El-Minia governorate, Egypt

Yazılıtaş¹,

Rehab²,

Gamal³

et al. 2016

Afr. J. Microbiol. Res.

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Egypt is considered one of the high-burden countries in WHO's Eastern Mediterranean region. This study determined the sociodemographic, microbial and phylogentic characteristics for Mycobacterium tuberculosis cases diagnosed in El-Minia governorate in upper Egypt. Fifty clinical samples were collected (male-to-female sex ratio 1.5 and 50% within the 21-to 40-years old) with complete history of patients; samples were cultured and identified by biochemical tests. DNA was extracted and tested for plc gene. Seven isolates were subjected to sequencing analysis of the amplified plc fragment and a phylogentic tree for these strains was formed. Out of 50 samples, 24 samples were culture positive, all grown isolates were identified as M. tuberculosis according to physical characters, rate of growth, biochemical tests. Direct polymerase chain reaction (PCR) method based on the amplification of 350 bp region of plc gene was used for the detection of M. tuberculosis, to differentiate it from Mycobacterium bovis in clinical samples. It was found that all isolates were positive for plc gene. Direct sequencing of 350 bp region of plc gene revealed many substitution mutations along the entire sequenced fragment. The main cause for such condition may rely on inadequate treatment regimen. The phylogenetic tree of the seven sequenced isolates were classified into three distinct nodes. We concluded that all cases were positive for M. tuberculosis and most of them were from rural area. There was different substitution mutations in the plc gene which may be due to the intermittent treatment regimens that made the tested strains under stress resulting in mutation.

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Assessment of directly observed therapy short-course (DOTs) of tuberculosis in Dakahlia governorate chest hospitals from 2006 to 2011

Cited by 3 publications

References 9 publications

Retrospective study of pulmonary and extrapulmonary tuberculosis cases in Giza Governorate during the period of 2014–2018

Retrospective study of pulmonary and extrapulmonary tuberculosis cases in Giza Governorate during the period of 2014–2018

Tuberculosis situation in Ismailia governorate (2002–2012) before and after Direct Observed Therapy Short Course Strategy (DOTS)

Sociodemographic, microbial and phylogentic studies of Mycobacterium tuberculosis cases diagnosed in El-Minia governorate, Egypt

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