Assessment of anodized titanium implants bioactivity

El-Wassefy, Noha A.; Hammouda, Ibrahim M.; Habib, Nour A.; El-awady, Ghada Y.; Marzook, Hamdy

doi:10.1111/clr.12031

Cited by 25 publications

(21 citation statements)

References 23 publications

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“…This suggests that implant surface could be conditioned by different procedures. It is shown that both organic and inorganic impurities on the surface can increase WCA, so different decontamination technique were investigated [49]. On titanium surface exposed to UV-A treatment was observed a superhydrophilicity behavior, due to an increased anatase surface modifications [50].…”

Section: Discussionmentioning

confidence: 99%

The Surface Anodization of Titanium Dental Implants Improves Blood Clot Formation Followed by Osseointegration

et al. 2018

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Abstract:The anodization of titanium dental implant influences the biologic processes of osseointegration. 34 grit-blasted and acid-etched titanium specimens were used to evaluate microand nano-roughness (R a ), contact angle (θ) and blood clot extension (bce). 17 samples were anodized (test) while the remaining were used as control. The bce, was measured using 10 µL of human blood left in contact with titanium for 5 min at room temperature. The micro-and nano-scale R a were measured under CLSM and AFM, respectively, while the θ was analyzed using the sessile drop technique. The bone-implant contact (BIC) rate was measured on two narrow implants retrieved for fracture. bce was 42.5 (±22) for test and 26.6% (±13)% for control group (p = 0.049). The micro-R a was 6.0 (±1.5) for the test and 5.8 (±1.8) µm for control group (p > 0.05). The θ was 98.5 • (±18.7 • ) for test and 103 • (±15.2 • ) for control group (p > 0.05). The nano-R a was 286 (±40) for the test and 226 (±40) nm for control group (p < 0.05). The BIC rate was 52.5 (±2.1) for test and 34.5% (±2.1%) for control implant (p = 0.014). (Conclusions) The titanium anodized surface significantly increases blood clot retention, significantly increases nano-roughness, and favors osseointegration. When placing dental implants in poor bone quality sites or with immediate loading protocol anodized Ti6Al4V dental implants should be preferred.

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Section: Discussionmentioning

confidence: 99%

The Surface Anodization of Titanium Dental Implants Improves Blood Clot Formation Followed by Osseointegration

et al. 2018

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“…Another common treatment for obtaining smooth sized features is acid‐etching (Herrero‐Climent et al, ; Medvedev et al, ; Saulacic, Erdosi, Bosshardt, Gruber, & Buser, ; Wennerberg, Svanborg, Berner, & Andersson, ). After performing dissolution of the original oxide layer, the selective dissolution of the substrate grains results in the acid etching process (El‐wassefy, Hammouda, Habib, El‐Awady, & Marzook, ). Natural passivation completes alongside exposing at ambient conditions to ensure the final surface roughness remains between 0.2 μm and 2 m (Zhao et al, ).…”

Section: Osteobiologic Materialsmentioning

confidence: 99%

Advances in osteobiologic materials for bone substitutes

Hasan

Byambaa

Morshed

et al. 2018

J Tissue Eng Regen Med

106

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A significant challenge in the current orthopedics is the development of suitable osteobiologic materials that can replace the conventional allografts, autografts, and xenografts and thereby serve as implant materials as bone substitutes for bone repair or remodelling. The complex biology behind the nanostructure and microstructure of bones and their repair mechanisms, which involve various types of chemical and biomechanical signalling amongst different cells, has set strong requirements for biomaterials to be used in bone tissue engineering. This review presents an overview of various types of osteobiologic materials to facilitate the formation of the functional bone tissue and healing of the bone, covering metallic, ceramic, polymeric, and cell-based graft substitutes, as well as some biomolecular strategies including stem cells, extracellular matrices, growth factors, and gene therapies. Advantages and disadvantages of each type, particularly from the perspective of osteoinductive and osteoconductive capabilities, are discussed. Although the numerous challenges of bone regeneration in tissue engineering and regenerative medicine are yet to be entirely addressed, further advancements in osteobiologic materials will pave the way towards engineering fully functional bone replacement grafts.

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“…The anodization processing of cpTi in the time range from 15 minutes to 120 minutes leads to the formation of a nanotubular oxide layer with limited thickness of about 2 μm after 120 minutes [14]. However, increasing anodizing time leads to decreasing the thickness of the nanotube wall [15].The nanotubular oxide layers formed on the titanium-based materials are compiled of the elements in the base material. For instance, nanotubular oxide layer formed on the Ti-Al alloy is composed of TiO2 and Al2O3.…”

Section: Fig 2 Formation Of the Oxide Layer On The Titanium Surfacementioning

confidence: 99%

Characterisation of the nanotubular oxide layer formed on the ultrafine-grained titanium

Barjaktarević¹,

Rakin²,

Djokić³

2018

Metall Mater Eng

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Commercially pure titanium (cpTi) and titanium alloys are metallic implant materials usually used in dentistry and orthopaedics. In order to improve implant properties, Ti-based materials may be surface modified by different procedures. One of the most attractive methods is electrochemical anodization, as a method for obtaining nanotubular oxide layer on the material surface, aiming at improving mechanical, biological and corrosion properties of the metallic biomaterials. In the present study, ultrafine-grained titanium (UFG cpTi) was obtained by high pressure torsion (HPT) under a pressure of 4.1 GPa with a rotational speed of 0.2 rpm, up to 5 rotations at room temperature. In order to form homogeneous nanotubular oxide layer on the UFG cpTi, the electrochemical anodization was performed in phosphoric acid containing 0.5 wt. % of NaF electrolyte during anodizing times of 30, 60 and 90 minutes. The characterisation of thus formed nanotubes was performed using the scanning electron microscopy (SEM), while the surface topography was analysed using the atomic force microscopy (AFM). The results show that the electrochemical anodization process leads to an enhanced roughness of the surface. The mechanical behaviour of the UFG cpTi after the electrochemical anodization process is estimated using the nanoindentation technique. Obtained results show that anodized material has lower value of nanohardness than non-anodized material. Moreover, anodized UFG cpTi has lower modulus of elasticity than non-anodized UFG cpTi and the value is close to those observed in bones.

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Assessment of anodized titanium implants bioactivity

Abstract: Nanostructured surface titanium implants could be prepared by anodic oxidation with resultant accelerated bioactivity that may be recommended for early loading.

Cited by 25 publications

References 23 publications

The Surface Anodization of Titanium Dental Implants Improves Blood Clot Formation Followed by Osseointegration

The Surface Anodization of Titanium Dental Implants Improves Blood Clot Formation Followed by Osseointegration

Advances in osteobiologic materials for bone substitutes

Characterisation of the nanotubular oxide layer formed on the ultrafine-grained titanium

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