Assessing the COVID-19 diagnostic laboratory capacity in Indonesia in the early phase of the pandemic

Hendarwan, Harimat; Syachroni, Syachroni; Aryastami, Ni Ketut; Su’udi, Amir; Susilawati, Made; Despitasari, Mieska; Mulyani, Ully Adhie; Sumiarsih, Mimi; Puspandari, Nelly; Indrati, Agnes Rengga; Solikha, Dewi Amila; Riana, Dyah Armi

doi:10.4103/2224-3151.294307

Cited by 28 publications

(26 citation statements)

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“…In terms of estimated daily testing capacity (by mid-April 2020), DKI Jakarta had the highest capacity of ~548 analyses per day, followed by East Java (301), Yogyakarta (238), Central Java (200), and West Java (148) ( 18 ). Since the largest testing capacity was available on Java Island, these laboratories had the heavy burden of conducting sample analyses from other islands too.…”

Section: Covid-19 Diagnostic Laboratory Capacity In the Early Phase Of The Pandemicmentioning

confidence: 99%

“…Since the largest testing capacity was available on Java Island, these laboratories had the heavy burden of conducting sample analyses from other islands too. While the testing capacity had increased, it was still insufficient, given the COVID-19's rapid transmission, which led to the eventual involvement of private laboratories and state veterinary laboratories to cater for an ever-increasing laboratory testing need ( 18 ).…”

Section: Covid-19 Diagnostic Laboratory Capacity In the Early Phase Of The Pandemicmentioning

confidence: 99%

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Laboratory Readiness and Response for SARS-Cov-2 in Indonesia

Aisyah

Mayadewi²,

Igusti³

et al. 2021

Front. Public Health

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The laboratory diagnosis of SARS-CoV-2 infection comprises the informational cornerstone in the effort to contain the infections. Therefore, the ability to leverage laboratories' capacity in diagnostic testing and to increase the number of people being tested are critical. This paper reviews the readiness of Indonesian laboratories during the early months of the pandemic. It discusses the success of cross-sectoral collaboration among previously siloed national and sub-national government institutions, international development agencies, and private sector stakeholders. This collaboration managed to scale-up the COVID-19 referral laboratory network from one Ministry of Health NIHRD laboratory in the capital to 685 laboratories across 34 provinces. However, this rapid growth within 12 months since the first Indonesian case was discovered remained insufficient to cater for the constantly surging testing demands within the world's fourth most populous country. Reflecting on how other countries built their current pandemic preparedness from past emergencies, this paper highlights challenges and opportunities in workforce shortage, logistic distribution, and complex administration that need to be addressed.

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Section: Covid-19 Diagnostic Laboratory Capacity In the Early Phase Of The Pandemicmentioning

confidence: 99%

Section: Covid-19 Diagnostic Laboratory Capacity In the Early Phase Of The Pandemicmentioning

confidence: 99%

Laboratory Readiness and Response for SARS-Cov-2 in Indonesia

Aisyah

Mayadewi²,

Igusti³

et al. 2021

Front. Public Health

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“…Here, we devised a method to evaluate an incoming kit for its suitability in the Indonesian market, where molecular testing is a new field for most medical communities. Local COVID-19 testing facility face constraints primarily from lack of reagents and equipment, and limited human resources(12). It is recommended to start with deriving kit specifications from their respective IFU (Table 1 and 2).…”

Section: Discussionmentioning

confidence: 99%

Comparison study of commercial COVID-19 RT-PCR kits propose an approach to evaluate their performances

Krismawati

Mahendra²,

Hartanto³

et al. 2021

Preprint

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With the increasing number of COVID-19 cases in Indonesia, scalable and high-throughput diagnostic testing is essential nationwide. Currently, RT-PCR has been the preferred method of viral detection and many manufacturers offer commercial kits for routine clinical diagnostics. In response to the incoming of various kits, there is a need to assess their performance and compatibility of use in clinical laboratories. Kit characteristics impact the testing workflow of these laboratories and some factors can render a kit to perform sub-optimally, leading to false results that are misleading for public safety. Here, we evaluated six commercial kits that are predominantly distributed to appointed testing facilities across Indonesia. Their performance was assessed based on their ease of use, availability, robustness and accuracy for scalable testing in a manual set-up. Our findings demonstrated that all six kits are suitable for use in routine diagnostics, but their considerations for use may vary according to different use-cases. To better guide considerations in procurement of kits, our study provided a systematic approach for laboratories to assess the performance of new incoming kits.

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“…A similar assessment at this data collection focusing on the laboratory capacity has published at the other journal. 6 We conducted primary data collection to check the current availability of all equipment under study. The variables examined in this study were the availability and the requirements of the necessary materials such as reagents, viral transport media (VTM), and Dacron swab.…”

Section: Methodsmentioning

confidence: 99%

“…This study kept going to leverage the need for human resources in escalating the laboratory capacity during the surge of Covid-19 pandemics as already published in the other journal. 6 Funding Indonesia's government budget supported this study through the NIHRD, MoH of the Republic of Indonesia.…”

Section: Study Limitationmentioning

confidence: 99%

Laboratory preparedness to support the Covid-19 pandemic respond in Indonesia

Mulyani¹,

Su’udi²,

Setiawaty³

et al. 2020

hsji

Self Cite

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Latar belakang: Penyakit jenis baru COVID-19 yang disebabkan oleh virus corona menjadi sebuah pandemic di akhir tahun 2019. Kota Wuhan (China) merupakan lokasi pertama terdeteksinya kasus COVID-19. Tanpa adanya kecurigaan apapun penyakit ini dengan cepatnya menyebar ke seluruh dunia mengikuti alur mobilitas manusia. Dalam kondisi tersebut sistem kesehatan di setiap negara tampak kelabakan khususnya dalam pengendalian transmisi penyakit. Studi ini ingin mengidentifikasi kesiapan jejaring laboratorium kesehatan di Indonesia. Metode: Penilaian cepat dilakukan terhadap ketersediaan dan kesiapan laboratoriaum dalam pennanganan pandemi Covid-19. Pengumpulan data dilakukan melalui pengisian questioner yang dikirim secara elektronik. Waktu pelaksanaan adalah minggu ketiga dan keempat, Maret 2020. Terdapat 44 laboratorium jejaring laboratorium dibawah Kementerian Kesehatan yang menjadi subjek penelitian, dan sebanyak 33 yang merespon secara lengkap Variabel ketersediaan, kecukupan dan kebutuhan bahan dan alat. Hasil: Jejaring laboratorium kesehatan dibawah Kementerian Kesehatan sudah terbentuk sejak tahun 2009. Dengan terjadinya pandemic COVID-19 Surat Keputusan Menteri Kesehatan telah direvisi hingga dua kali agar dapat meningkatkan kapasitas dan memperluas jejaring ke seluruh wilayah NKRI. Hasil studi menunjukkan, laboratorium jejaring dibawah Kementerian Kesehatan belum siap dalam menghadapi pandemic COVID-19. Dua jenis laboratorium jejaring yaitu laboratorium surveillans maupun laboratorium diagnostic memiliki kondisi yang sama. Ketersediaan bahan dan alat laboratorium standar masih tergolong rata-rata, bahkan dari sisi kecukupannyapun masih jauh dibawah kapasitas kebutuhan dalam penanganan specimen COVID-19. Kondisi yang sama juga tampak untuk bahan pendukung laboratorium termasuk alat pelindung diri untuk petugas. Kesimpulan: Kesiapan laboratorium sebagai bagian dari system kesehatan dalam kondisi pandemic masih lemah. Keberadaan alat penunjang diagnose khususnya untuk penyakit menular harus dilengkapi sesuai dengann type laboratorium. Pandemi COVID-19 menjadi alarm dalam menghadapi era baru dan antisipasi masalah dimasa yang akan datang. Kata kunci: Kesiapan laboratorium, COVID-19, Indonesia Abstract Background: A novel coronavirus disease called COVID-19 has become pandemic in late 2019. Wuhan City was the first place detected as the source of the pandemic. Without suspicion, it spreads over the world, along with human mobility. In such a condition, every country seems quite stuttering to prepare its health system to prevent its people from the possible transmission. This paper aims to describe the preparedness of the networking laboratory in Indonesia. Methods: We conducted a rapid assessment of laboratory availability and preparedness to respond to the Covid-19 pandemic. We held the data collection on the third and fourth week of March 2020 by sending an electronic questionnaire to all 44 networking laboratories under the Ministry of Health structure. The variables assessed in this study were the availability and the requirements of the Covid-19 related laboratory's substances, including reagents and other equipment types. Results: The Ministry of Health established the networking laboratory in 2009, but due to the COVID-19 pandemic, it has renewed twice to enhance and expand the laboratory capacities over the country. Our studies showed preparedness among networking laboratories in Indonesia regarding this new emerging COVID-19 condition was quite devastating. Both surveillance and diagnostic laboratories have a similar situation. The availability of their primary materials was mediocre, but the adequacy was far beyond the capacity in handling the COVID-19 specimen. We found a similar case in the laboratory, supporting materials, and personal protective equipment (PPE). Conclusion: Laboratory preparedness during initial period of time of the COVID-19 pandemic as part of the health system is still weak. The availability of the necessary equipment, supporting materials, and personal protective equipment are far beyond the requirements. The COVID-19 has alarmed the laboratory and the whole health system in Indonesia into a new era with better future preparedness. Keywords: laboratory preparedness, COVID-19, Indonesia

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Assessing the COVID-19 diagnostic laboratory capacity in Indonesia in the early phase of the pandemic

Cited by 28 publications

References 0 publications

Laboratory Readiness and Response for SARS-Cov-2 in Indonesia

Laboratory Readiness and Response for SARS-Cov-2 in Indonesia

Comparison study of commercial COVID-19 RT-PCR kits propose an approach to evaluate their performances

Laboratory preparedness to support the Covid-19 pandemic respond in Indonesia

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