Aspiration Cytodiagnosis of Lid Tumors

Cytomorphologic Features of Sebaceous Carcinoma on Fine Needle Aspiration

“…Cytologic features of sebaceous carcinoma have been reported in a limited number of cases. 1,3,5,[7][8][9][10] We report three cases of metastatic sebaceous carcinoma diagnosed by fine needle aspiration (FNA).…”

Cytomorphologic Features of Sebaceous Carcinoma on Fine Needle Aspiration

“…Cytologic features of sebaceous carcinoma have been reported in a limited number of cases. 1,3,5,[7][8][9][10] We report three cases of metastatic sebaceous carcinoma diagnosed by fine needle aspiration (FNA).…”

Cytologic Features of Metastatic Sebaceous Carcinoma: Report of Two Cases With Comparison to Three Cases of Basal Cell Carcinoma

“…Fineneedle aspiration has proven to be a useful technique in identifying recurrences and metastatic disease in patients with a known primary sebaceous carcinoma. [3][4][5][6][7][8][9][10] Sebaceous carcinoma was first described in 1956 by Straatsma, 13 and since then the literature contains numerous case reports and series which describe the histological features of sebaceous carcinoma. 1,13,14 There are, however, fewer than 20 cases which report morphologic features of this tumor in FNAB smears in the literature.…”

“…1,13,14 There are, however, fewer than 20 cases which report morphologic features of this tumor in FNAB smears in the literature. [3][4][5][6][7][8][9][10][11] Hood et al 9 first described in detail the characteristic cytologic findings of sebaceous carcinomas, which included cohesive clusters of moderately atypical large cells with characteristic moderate amounts of cytoplasm with varying degrees of vacuolization, showing intracellular globules of lipid material on oil-red O. Other case reports, as well as our two cases, exhibited similar cytologic findings.…”

Fine Needle Capillary Sampling of Eyelid Masses

“…The final diagnosis should be reached after a collaborative assessment of the cytologic findings with the clinical findings. 17 In the literature the diagnostic accuracy of cytologic diagnosis of orbital lesions ranges from 93% to 100%, and the accuracy of differentiating benign from malignant lesions ranges from 50% to 100%. 7,20,24 The accuracy in this study is attributable to the fact that all aspiration was done by cytopathologists, allowing them to obtain a better idea of the clinical presentation, and to close collaboration between the ophthalmologist and cytologists.…”

“…1 For example, a distinction between BCC and SC is essential because the former is locally invasive, whereas the latter is capable of metastases, is associated with a pagetoid spread and has to be managed by a wide surgical excision. 17 A distinction between primary and secondary tumors is also important to decide whether surgical intervention is necessary. 4,12,36 Metastatic tumors may involve the eye, orbit or extraocular muscles as well as eyelid and may be far more common than generally believed.…”

Cytomorphologic Features of Sebaceous Carcinoma on Fine Needle Aspiration

“…Cytologic features of sebaceous carcinoma have been reported in a limited number of cases. 1,3,5,[7][8][9][10] We report three cases of metastatic sebaceous carcinoma diagnosed by fine needle aspiration (FNA).…”

Cytologic Features of Metastatic Sebaceous Carcinoma: Report of Two Cases With Comparison to Three Cases of Basal Cell Carcinoma

“…Fineneedle aspiration has proven to be a useful technique in identifying recurrences and metastatic disease in patients with a known primary sebaceous carcinoma. [3][4][5][6][7][8][9][10] Sebaceous carcinoma was first described in 1956 by Straatsma, 13 and since then the literature contains numerous case reports and series which describe the histological features of sebaceous carcinoma. 1,13,14 There are, however, fewer than 20 cases which report morphologic features of this tumor in FNAB smears in the literature.…”

“…1,13,14 There are, however, fewer than 20 cases which report morphologic features of this tumor in FNAB smears in the literature. [3][4][5][6][7][8][9][10][11] Hood et al 9 first described in detail the characteristic cytologic findings of sebaceous carcinomas, which included cohesive clusters of moderately atypical large cells with characteristic moderate amounts of cytoplasm with varying degrees of vacuolization, showing intracellular globules of lipid material on oil-red O. Other case reports, as well as our two cases, exhibited similar cytologic findings.…”

Fine Needle Capillary Sampling of Eyelid Masses

“…The final diagnosis should be reached after a collaborative assessment of the cytologic findings with the clinical findings. 17 In the literature the diagnostic accuracy of cytologic diagnosis of orbital lesions ranges from 93% to 100%, and the accuracy of differentiating benign from malignant lesions ranges from 50% to 100%. 7,20,24 The accuracy in this study is attributable to the fact that all aspiration was done by cytopathologists, allowing them to obtain a better idea of the clinical presentation, and to close collaboration between the ophthalmologist and cytologists.…”

“…1 For example, a distinction between BCC and SC is essential because the former is locally invasive, whereas the latter is capable of metastases, is associated with a pagetoid spread and has to be managed by a wide surgical excision. 17 A distinction between primary and secondary tumors is also important to decide whether surgical intervention is necessary. 4,12,36 Metastatic tumors may involve the eye, orbit or extraocular muscles as well as eyelid and may be far more common than generally believed.…”

Cytomorphologic Features of Sebaceous Carcinoma on Fine Needle Aspiration

“…Cytologic features of sebaceous carcinoma have been reported in a limited number of cases. 1,3,5,[7][8][9][10] We report three cases of metastatic sebaceous carcinoma diagnosed by fine needle aspiration (FNA).…”

Cytologic Features of Metastatic Sebaceous Carcinoma: Report of Two Cases With Comparison to Three Cases of Basal Cell Carcinoma

“…Fineneedle aspiration has proven to be a useful technique in identifying recurrences and metastatic disease in patients with a known primary sebaceous carcinoma. [3][4][5][6][7][8][9][10] Sebaceous carcinoma was first described in 1956 by Straatsma, 13 and since then the literature contains numerous case reports and series which describe the histological features of sebaceous carcinoma. 1,13,14 There are, however, fewer than 20 cases which report morphologic features of this tumor in FNAB smears in the literature.…”

“…1,13,14 There are, however, fewer than 20 cases which report morphologic features of this tumor in FNAB smears in the literature. [3][4][5][6][7][8][9][10][11] Hood et al 9 first described in detail the characteristic cytologic findings of sebaceous carcinomas, which included cohesive clusters of moderately atypical large cells with characteristic moderate amounts of cytoplasm with varying degrees of vacuolization, showing intracellular globules of lipid material on oil-red O. Other case reports, as well as our two cases, exhibited similar cytologic findings.…”

Fine Needle Capillary Sampling of Eyelid Masses

“…The final diagnosis should be reached after a collaborative assessment of the cytologic findings with the clinical findings. 17 In the literature the diagnostic accuracy of cytologic diagnosis of orbital lesions ranges from 93% to 100%, and the accuracy of differentiating benign from malignant lesions ranges from 50% to 100%. 7,20,24 The accuracy in this study is attributable to the fact that all aspiration was done by cytopathologists, allowing them to obtain a better idea of the clinical presentation, and to close collaboration between the ophthalmologist and cytologists.…”

“…1 For example, a distinction between BCC and SC is essential because the former is locally invasive, whereas the latter is capable of metastases, is associated with a pagetoid spread and has to be managed by a wide surgical excision. 17 A distinction between primary and secondary tumors is also important to decide whether surgical intervention is necessary. 4,12,36 Metastatic tumors may involve the eye, orbit or extraocular muscles as well as eyelid and may be far more common than generally believed.…”