Aspergillus Otomycosis in an Immunocompromised Patient

Rutt, Amy L; Sataloff, Robert T.

doi:10.1177/014556130808701107

Cited by 25 publications

(34 citation statements)

References 12 publications

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“…Otolaryngologists should remain alert for detection of otomycosis and should consider obtaining culture when this disease is suspected. The findings in this study are in general agreement with the findings observed by earlier workers like Rutt et al [35] and Ozcan et al [36].…”

Section: Discussionsupporting

confidence: 94%

Presentation Pattern and Fungal Agents Spectrum Causing Otommycosis

Dekhil

2018

Asian J Pharm Clin Res

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Objective: This study was aimed to identify the public pattern of presentation, influencing factors, and sort the fungal species, distribution of sex of patients with otomycosis.Results: The predominant complaints were pruritus and found in 76 patients (88.73%), discomfort and pain found in 62 patients (72.09%), aural fullness in 48 patients (55.81%), tinnitus in 34 patients (39.53%), hearing impairment in 50 cases (58.31%), ear discharge in 22 patients (25.58%), and most of the symptoms seen in 36 patients (68.14%). The results showed a total of eight fungal species belong to six different genera, namely, Aspergillus, Candida, Penicillium, Rhizopus, Alternaria, and Cephalosporium were isolated during this study. Among identified fungi, Aspergillus niger was found to be the most prevalent fungal species with 35.71% followed by Candida albicans (27.55%), Aspergillus flavus (10.20%), Aspergillus fumigatus (8.16), Penicillium digitatum (6.12%) and Cephalosporium species (4.08%), and Rhizopus species (5.1%), while Alternaria alternata had the lowest percentage (6.54%).Conclusion: Otomycosis/mycotic otitis externa is still a common problem and there is a rise in the occurrence of otomycosis in latest years, especially in tropical and subtropical humid climates.

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Section: Discussionsupporting

confidence: 94%

Presentation Pattern and Fungal Agents Spectrum Causing Otommycosis

Dekhil

2018

Asian J Pharm Clin Res

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“…Tympanic membrane perforation may occur as a complication of otomycosis that starts in an ear with an intact ear drum. 3 In the study by Rama Kumar, the incidence of tympanic membrane perforation in otomycosis was found to be 11%. 15 He also stated that perforations were more common with otomycosis caused by C albicans.…”

Section: Discussionmentioning

confidence: 99%

“…1 In immunocompromised patients, treatment of otomycosis should be vigorous to prevent complications such as hearing loss and invasive temporal bone infection. 3 We conducted a comparative clinical study involving 50 immunocompetent and 50 immunocompromised patients with otomycosis. Clinical presentation, predisposing factors, mycologic profile, and treatment outcomes were compared.…”

Section: Introductionmentioning

confidence: 99%

Otomycosis in Immunocompetent and Immunocompromised Patients: Comparative Study and Literature Review

2012

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A comparative clinical study was carried out that included 50 cases of otomycosis in immunocompetent patients and 50 cases of otomycosis in immunocompromised patients. Clinical presentation, predisposing factors, mycologic profile, and treatment outcomes were compared. Aspergillus spp were the most commonly isolated fungi in the immunocompetent group, and Candida albicans in the immunocompromised group. Bilateral involvement was more common in the immunocompromised group. All the patients were treated with topical clotrimazole ear drops. Four patients in the immunocompromised group did not respond to treatment with clotrimazole but were treated successfully with fluconazole ear drops. Three patients had a small tympanic membrane perforation due to otomycosis.

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“…The mechanism of perforation has been attributed to mycotic thrombosis of the tympanic membrane blood vessels resulting in avascular necrosis of tympanic membrane 5,17. There may not be any clinical features predictive of tympanic membrane perforation.…”

Section: Introductionmentioning

confidence: 99%

Fungal Infections of the Ear in Immunocompromised Host: A Review

Viswanatha¹,

Naseeruddin²

2011

Mediterr J Hematol Infect Dis

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Otomycosis is a fungal infection of the external ear; middle ear and open mastoid cavity.1 Meyer first described the fungal infection of the external ear canal in 1884. External ear canal has an ideal warm humid environment for the proliferation of fungus.2 Although this disease is rarely life threatening, it can presents a challenging and frustrating situation for the otologist and patients due to long term treatment and high rate of recurrence.3 Otomycosis is seen more frequently in immunocompromised patients as compared to immunocompetent persons. Recurrence rate is high in immunocompromised patients and they need longer duration treatment and complications are more frequent in immunocompromised patients.In the recent years; opportunistic fungal infections are gaining greater importance in human medicine as a result of possibly huge number of immunocompromised patients.4 In immunocompromised patients, it is important that the treatment of otomycosis be vigorous, to minimize complications such as hearing loss, tympanic membrane perforations and invasive temporal bone infection.5 Fungal cultures are essential to confirm the diagnosis.Hematological investigations play a very important role in confirming the diagnosis and immunity status of the patients. In diabetic patients with otomycosis, along with antifungal therapy, blood sugar levels should be controlled with medical therapy to prevent complications.

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Aspergillus Otomycosis in an Immunocompromised Patient

Cited by 25 publications

References 12 publications

Presentation Pattern and Fungal Agents Spectrum Causing Otommycosis

Presentation Pattern and Fungal Agents Spectrum Causing Otommycosis

Otomycosis in Immunocompetent and Immunocompromised Patients: Comparative Study and Literature Review

Fungal Infections of the Ear in Immunocompromised Host: A Review

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