Askin's Tumor: A Dual Case Study

Shrestha, Bikal; Kapur, Bhupendra Nath; Karmacharya, Kavita; Kakkar, Sunita; Ghuliani, Ranjit

doi:10.1155/2011/252196

Cited by 7 publications

(6 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…According to classification of tumors of the nervous system, Askin's tumor is a member of the Ewing's sarcoma family of tumors/peripheral PNETs. The clinical occurrence of Askin's tumor is rare and only a limited number of cases have been documented (6)(7)(8)(9)(10)(11). The present study reported 11 cases of Askin's tumor, a relatively large sample size in terms of its incidence rate.…”

Section: Discussionmentioning

confidence: 56%

Askin's tumor: 11 cases and a review of the literature

Zhang

Lu²,

Zhang³

et al. 2015

Oncology Letters

View full text Add to dashboard Cite

Abstract. Askin's tumor is a peripheral primitive neruoectodermal tumor within the thoracopulmonary region, which primarily occurs in children and young adults. In addition, Askin's tumor is commonly misdiagnosed, as it is rare and easily mistaken for other small round-cell tumors. The present study aimed to investigate the clinical characteristics, prognostic factors and treatment outcomes of patients diagnosed with Askin's tumor. Computed tomography (CT) scans, histopathology and immunohistochemical analysis were used for diagnosis. Patients were treated with combined (surgery-chemotherapy-radiotherapy) or mono-therapy (chemotherapy or radiotherapy) methods. A total of 11 consecutive patients with Askin's tumor (aged 8-22 years) were treated at the First Affiliated Hospital of Zhengzhou University between April 2010 and June 2013; nine patients underwent combined therapy and two patients were treated using mono-therapy. Chest lumps, swelling and pain were the most common presenting symptoms. Patients were followed up for ≤24 months post surgery and the results revealed that the median survival time of the combined and mono-therapy treatment groups were 15 and 7 months, respectively. Primary tumor size, metastasis, lactate dehydrogenase indicators and tumor stages were found to be important prognostic factors affecting patient outcome. In conclusion, the results of the present study demonstrated that the combination of surgery, chemotherapy and radiotherapy resulted in the optimal outcome for Askin's tumor patients.

show abstract

Section: Discussionmentioning

confidence: 56%

Askin's tumor: 11 cases and a review of the literature

Zhang

Lu²,

Zhang³

et al. 2015

Oncology Letters

View full text Add to dashboard Cite

show abstract

“…El dolor local podría estar presente y disminuir en las noches pero no desaparecer completamente. Puede presentarse con parestesia local y raramente con fractura patológica o síntomas de metástasis relacionados [7]. Relacionado con el paciente presentado.…”

Section: Discussionunclassified

Caso Clínico: Tumor de Askin.

et al. 2017

View full text Add to dashboard Cite

ResumenIntroducción: El tumor neuroectodérmico primitivo (PNET) de la pared torácica también denominado tumor de Askin es una neoplasia rara y agresiva, que afecta mayoritariamente a niños y adolescente.Caso Clínico: Se reporta el caso de un joven de 17 años que presentó una gran tumoración subescapular derecha, acompañado de dolor y disnea a quien realizó previa quimioterapia neoadyuvante y dada buena repuesta, resección tumoral con márgenes oncológicos más reconstrucción plástica de hemitórax derecho. Constatándose como hallazgo intraoperatorio, no evidente en imágenes, metástasis pulmonar. Presenta evolución favorable posquirúrgica con posterior recurrencia local y metástasis a distancia, sin respuesta a la quimioterapia adyuvante con fallecimiento 7 meses luego de la cirugía.Conclusión: En el presente caso el TA tuvo una sobrevida corta a pesar el tratamiento neoadyuvante, resección quirúrgica y nuevo ciclo de tratamiento quimioterápico.Palabras Claves: TUMORES NEUROECTODÉRMICOS PERIFÉRICOS PRIMITIVOS, TÓRAX, SUPERVIVENCIA (SALUD PÚBLICA), QUIMIOTERAPIA COMBINADA. AbstractIntroduction: The primitive neuroectodermal tumor (PNET) of the thoracic wall also called Askin's tumor is a rare and aggressive neoplasm, affecting mainly children and adolescents.Clinical case: We report the case of a 17-year-old boy who presented a large right subscapular tumor, accompanied by pain and dyspnea who underwent previous neoadjuvant chemotherapy and given good response, tumor resection with oncological margins plus plastic reconstruction of the right hemithorax. Being confirmed as an intraoperative finding, not evident in images, pulmonary metastasis. It presents favorable postoperative evolution with subsequent local recurrence and distant metastasis, without response to adjuvant chemotherapy with death 7 months after surgery.

show abstract

“…Algunas tiroides ectópicas linguales se manifiestan con cuadros obstructivos con disfagia y disfonía, hemorragia y función endócrina normal o alterada [1]. Se precisa realizar diagnóstico diferencial con hemangiomas, linfomas, fibromas, abscesos y tumores malignos de la lengua [7]. Casos de tiroides ectópica lingual son diagnosticados de forma incidental con métodos de imagen [3,6].…”

Section: Introductionunclassified

Tiroides Lingual Ectópica en Paciente Adulta Hipotiroidea. Diagnóstico Casual por Tomografía Computarizada

Sánchez

Martinod

García³

et al. 2019

Rev. Oncol. Ecu.

View full text Add to dashboard Cite

ResumenIntroducción: Los casos de tiroides ectópica localizados en la base de la lengua son anormalidades congénitas raras y difíciles de diagnosticar. Razón de presentación del caso.Caso Clínico: El caso corresponde a una mujer de 41 años con tiroides en base de la lengua diagnosticada incidentalmente con tomografía computarizada (TC), con antecedentes de hipotiroidismo y cáncer de mama derecha. Al examen físico de cuello no se palpa glándula tiroidea ni se observa masa o protuberancia en cavidad bucal. Por control del cáncer de mama, se solicita tomografía por emisión de positrones (PET) y ecografía de cuello, reportándose captación del radiofármaco en la región cervical anterior y superior de cuello, y ausencia de tejido glandular tiroideo a nivel habitual, respectivamente. Por cuanto, se realiza TC simple y contrastada observándose a nivel de la raíz de la lengua una imagen nodular hipercaptante que mide 23x20x20 mm, bien definida, contornos regulares, no infiltra tejidos adyacentes, impronta luz de la orofaringe, sin individualizar la glándula tiroides a nivel habitual, corroborando así el diagnóstico de tiroides ectópica lingual.Conclusión: El diagnóstico de tiroides ectópica en paciente adulto hipotiroideo es raro, por lo que debe considerarse la realización de TC si al examen físico y ecográfico no es palpable ni observable.Palabras Claves: DISGENESIAS TIROIDEAS, TIROIDES LINGUAL, TOMOGRAFÍA COMPUTARIZADA POR RAYOS X, ECUADOR. Copyright Tufiño, et al. Este artículo es distribuido bajo los términos de Creative Commons Attribution License 4.0 , el cual permite el uso y redistribución citando la fuente y al autor original. AbstractIntroduction: Cases of ectopic thyroid located at the base of the tongue are rare and difficult to diagnose congenital abnormalities. Reason for presenting the case.Clinical case: The case corresponds to a 41-year-old woman with thyroid based on the tongue diagnosed incidentally with computed tomography (CT), with a history of hypothyroidism and right breast cancer. On the physical examination of the neck, the thyroid gland is not palpated, and no mass or bump is observed in the oral cavity. For breast cancer control, positron emission tomography (PET) and neck ultrasound are requested, radiopharmaceutical uptake is reported in the anterior and upper cervical neck region, and absence of thyroid glandular tissue at the usual level, respectively. As a simple and contrasted CT scan, a hypercapting nodular image measuring 23x20x20 mm, well defined, regular contours is observed at the root of the tongue, does not infiltrate adjacent tissues, oropharynx light imprint, without individualizing the thyroid gland to usual level, thus corroborating the diagnosis of lingual ectopic thyroid.Conclusion: The diagnosis of ectopic thyroid in an adult hypothyroid patient is rare, so CT should be considered if the physical and ultrasound examination is not palpable or observable.

show abstract

Askin's Tumor: A Dual Case Study

Cited by 7 publications

References 15 publications

Askin's tumor: 11 cases and a review of the literature

Askin's tumor: 11 cases and a review of the literature

Caso Clínico: Tumor de Askin.

Tiroides Lingual Ectópica en Paciente Adulta Hipotiroidea. Diagnóstico Casual por Tomografía Computarizada

Contact Info

Product

Resources

About