1957
DOI: 10.1017/s0022172400037360
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Abstract: Eleven cases of aseptic meningitis occurred in a Cambridgeshire village between 17 October and 11 November 1955. The syndrome consisted of severe headache, backache, vomiting, fever and neck stiffness together with lymphocytes and frequently some granulocytes in the cerebrospinal fluid. Principally, it affected persons aged between 10 and 30 years. Out of a total population twenty-three at risk, seventeen were infected and eight became ill. A further three contacts who were living in Cambridge became ill.Ident… Show more

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Cited by 12 publications
(2 citation statements)
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“…The following year outbreaks occurred in East Anglia (Garnett et al 1957), the virus being isolated from cerebrospinal fluids, throat washings and faeces of patients. In 1956 there were widespread outbreaks (Tyrell & Snell, 1956 ; Lyle 1956 : Rotem 1957 : Boissard et al 1957 : McLean & Cameron 1957 : Galpine et al 1958 : Jamieson et al 1958: Stones 1958). ECHO virus type 9 was at this time widely prevalent throughout Europe (Nihoul & Querin‐Thiry 1957 : Johnsson 1957) and in Canada (Sultanian & Rhodes 1958).…”
Section: Viruses Which Affect Manmentioning
confidence: 99%
“…The following year outbreaks occurred in East Anglia (Garnett et al 1957), the virus being isolated from cerebrospinal fluids, throat washings and faeces of patients. In 1956 there were widespread outbreaks (Tyrell & Snell, 1956 ; Lyle 1956 : Rotem 1957 : Boissard et al 1957 : McLean & Cameron 1957 : Galpine et al 1958 : Jamieson et al 1958: Stones 1958). ECHO virus type 9 was at this time widely prevalent throughout Europe (Nihoul & Querin‐Thiry 1957 : Johnsson 1957) and in Canada (Sultanian & Rhodes 1958).…”
Section: Viruses Which Affect Manmentioning
confidence: 99%
“…The association of this particular virus with aseptic meningitis, often accompanied by a rubelliform rash, was first observed in 1956 (Tyrrell and Snell, 1956;McLean and Cameron, 1957). On many subsequent occasions frank epidemics of meningitis, sharply circumscribed in time and place, have occurred with evidence of direct spread within families (Sanford and Sulkin, 1959;Sabin, Krumbiegal, and Wigand 1958;Sabin 1960).…”
mentioning
confidence: 98%