Arteriosclerosis in Parkinsonism

Abstract

Some textbooks on general and neurological medicine give the impression that cerebral arteriosclerosis is an important cause of Parkinsonism (e.g.,

Motor Neuron Disease and Parkinson's Disease Are Not Associated with Other Disorders at Autopsy

“…Arterial hypertension was less prevalent in Parkinson's disease, but this appeared due to the effect of the disease [6]. The role of arteriosclerosis has been debated, but no asso ciation was observed clinically [6] or pathologically [7]. The present data also indicated no excess of arteriosclerosis in autopsies of Parkinson's dis ease.…”

Motor Neuron Disease and Parkinson's Disease Are Not Associated with Other Disorders at Autopsy

“…Arterial hypertension was less prevalent in Parkinson's disease, but this appeared due to the effect of the disease [6]. The role of arteriosclerosis has been debated, but no asso ciation was observed clinically [6] or pathologically [7]. The present data also indicated no excess of arteriosclerosis in autopsies of Parkinson's dis ease.…”

Psychiatric symptoms in Parkinsonism.

“…In three cases non-senile organic and affective disorders were associated. Thus a large number of patients improved psychiatrically without physical improvement DISCUSSION Although the subdivision of cases of Parkinsonism according to their apparent pathological causes has been criticized, especially with regard to the arteriosclerotic type (Eadie and Sutherland, 1964), in this study it proved possible to divide the cases in this way and allocation to a diagnostic sub-category carried prognostic implications. The psychiatric findings confirm general clinical impressions and show the relative frequency of mental symptoms in the main types of Parkinsonism.…”

Different clinical and evolutional patterns in late idiopathic and vascular parkinsonism

“…Parkinsonism secondary to strokes has been described by many authors [2,4,6,26,30].However, the clinical and neuropathological identity of VP is still questionable [3,16,31], and there is the need to develop new criteria to improve the accuracy of diagnosis [24,32]. Some studies suggest that rare cases of parkinsonism may be related to cerebrovascular lesions without morphological signs of degenerative PD [8,12,18], while about 20-25 % of PD patients show additional signs of cerebrovascular disease [7,12].…”

Motor Neuron Disease and Parkinson's Disease Are Not Associated with Other Disorders at Autopsy

“…Arterial hypertension was less prevalent in Parkinson's disease, but this appeared due to the effect of the disease [6]. The role of arteriosclerosis has been debated, but no asso ciation was observed clinically [6] or pathologically [7]. The present data also indicated no excess of arteriosclerosis in autopsies of Parkinson's dis ease.…”

Psychiatric symptoms in Parkinsonism.

“…In three cases non-senile organic and affective disorders were associated. Thus a large number of patients improved psychiatrically without physical improvement DISCUSSION Although the subdivision of cases of Parkinsonism according to their apparent pathological causes has been criticized, especially with regard to the arteriosclerotic type (Eadie and Sutherland, 1964), in this study it proved possible to divide the cases in this way and allocation to a diagnostic sub-category carried prognostic implications. The psychiatric findings confirm general clinical impressions and show the relative frequency of mental symptoms in the main types of Parkinsonism.…”

Different clinical and evolutional patterns in late idiopathic and vascular parkinsonism

“…Parkinsonism secondary to strokes has been described by many authors [2,4,6,26,30].However, the clinical and neuropathological identity of VP is still questionable [3,16,31], and there is the need to develop new criteria to improve the accuracy of diagnosis [24,32]. Some studies suggest that rare cases of parkinsonism may be related to cerebrovascular lesions without morphological signs of degenerative PD [8,12,18], while about 20-25 % of PD patients show additional signs of cerebrovascular disease [7,12].…”

Motor Neuron Disease and Parkinson's Disease Are Not Associated with Other Disorders at Autopsy

“…Arterial hypertension was less prevalent in Parkinson's disease, but this appeared due to the effect of the disease [6]. The role of arteriosclerosis has been debated, but no asso ciation was observed clinically [6] or pathologically [7]. The present data also indicated no excess of arteriosclerosis in autopsies of Parkinson's dis ease.…”

Psychiatric symptoms in Parkinsonism.

“…In three cases non-senile organic and affective disorders were associated. Thus a large number of patients improved psychiatrically without physical improvement DISCUSSION Although the subdivision of cases of Parkinsonism according to their apparent pathological causes has been criticized, especially with regard to the arteriosclerotic type (Eadie and Sutherland, 1964), in this study it proved possible to divide the cases in this way and allocation to a diagnostic sub-category carried prognostic implications. The psychiatric findings confirm general clinical impressions and show the relative frequency of mental symptoms in the main types of Parkinsonism.…”

Different clinical and evolutional patterns in late idiopathic and vascular parkinsonism

“…Parkinsonism secondary to strokes has been described by many authors [2,4,6,26,30].However, the clinical and neuropathological identity of VP is still questionable [3,16,31], and there is the need to develop new criteria to improve the accuracy of diagnosis [24,32]. Some studies suggest that rare cases of parkinsonism may be related to cerebrovascular lesions without morphological signs of degenerative PD [8,12,18], while about 20-25 % of PD patients show additional signs of cerebrovascular disease [7,12].…”