Arch Derm Syphilol
 1938
DOI: 10.1001/archderm.1938.01480140038003
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Arsenical Dermatitis Produced in Treatment of Trichomonas Vaginitis

Beatrice Kesten1
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Cited by 7 publications

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“…Serious skin reactions of any kind have rarely been reported to follow the widespread use of acetarsol for trichomonal infection, although minor reactions are well recognized (Campbell, 1937;Long, 1937;Kesten, 1938 ;Prosser-Thomas, 1948;Doyle, 1952;Peck, 1954).…”
Section: Post-mortem Examination (48 Hours After Death)mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Serious skin reactions of any kind have rarely been reported to follow the widespread use of acetarsol for trichomonal infection, although minor reactions are well recognized (Campbell, 1937;Long, 1937;Kesten, 1938 ;Prosser-Thomas, 1948;Doyle, 1952;Peck, 1954).…”
Section: Post-mortem Examination (48 Hours After Death)mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…It is, however, an arsenical preparation and cases of sensitization have been reported. Most of these, which occurred after prolonged treatment with acetarsol vaginal pessaries or powder used intravaginally,.were manifested by a generalized exfoliative dermatitis, pyrexia, and malaise (Kesten, 1938;Doyle, 1952). Some patients had been previously sensitized by arsenical compounds for the treatment of syphilis and showed immediate symptoms of sensitization on beginning a subsequent course of acetarsol vaginal pessaries (Campbell, * Received for publication August 25, 1954August 25, .…”
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Michael (1929) reported a case of exfoliative dermatitis in a woman who had been treated with acetarsol for mucous colitis, and Nicolas and Rousset (1936) noted the occurrence of lesions resembling pityriasis rosea after injection with the same drug. Beatrice Kesten (1938) described five cases of sensitization following intravaginal therapy for trichomonas infestation with a powder containing acetarsol. Persistence in the treatment of these cases resulted in generalized dermatitis after warning signs in the form of a local erythema of the external genitalia and thighs.…”
Section: Commentmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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