2000
DOI: 10.1055/s-2000-12141 View full text |Buy / Rent full text
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Abstract: Our results demonstrate that Mg2+ sulfate administration regimens used in Group B and C reduce postoperative arrhythmic events in patients undergoing CABG.

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“…Plasma concentrations are decreased after abdominal 11,12 or orthopedic surgery. 13 After heart surgery, mean magnesemia is reduced, 14,15 and the frequency of hypomagnesemia increased from 19.2% preoperatively to 71% immediately after surgery before dropping slightly to 65.6% 24 hr later. 16 For Zuccala et al, the depletion of intracellular Mg would appear to be closely correlated with reduced serum concentrations.…”
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“…Plasma concentrations are decreased after abdominal 11,12 or orthopedic surgery. 13 After heart surgery, mean magnesemia is reduced, 14,15 and the frequency of hypomagnesemia increased from 19.2% preoperatively to 71% immediately after surgery before dropping slightly to 65.6% 24 hr later. 16 For Zuccala et al, the depletion of intracellular Mg would appear to be closely correlated with reduced serum concentrations.…”
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“…Various pharmacological agents have been used to treat or prevent AF after CABG. Several clinical trials have evaluated the use of magnesium sulfate to prevent AF after CABG 16–31 . These trials have advocated conflicting recommendations.…”
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“…In contrast, Nurozler et al [19] demonstrated a significant reduction in AF (from 20% to 4%) during the infusion of Mg for 5 days (100 mmol/5 days) [19]. Speziale et al [20] noted a complete elimination of AF in patients who received 1g of Mg in pump priming solution and the infusion of 10 mmol of MgSO 4 for the first 24 postoperative hours [20]. According to them such an administration kept the serum Mg concentration at an unchanged level during CPB and in the early postoperative period.…”
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