2010
DOI: 10.1186/1471-2407-10-181
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Abstract: BackgroundNeuroblastoma has successfully served as a model system for the identification of neuroectoderm-derived oncogenes. However, in spite of various efforts, only a few clinically useful prognostic markers have been found. Here, we present a framework, which integrates DNA, RNA and tissue data to identify and prioritize genetic events that represent clinically relevant new therapeutic targets and prognostic biomarkers for neuroblastoma.MethodsA single-gene resolution aCGH profiling was integrated with mic…

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