Arising of electrostatic charge in the mixing process and its influencing factors

Karner, Stefan; Urbanetz, Nora Anne

doi:10.1016/j.powtec.2012.04.062

Cited by 24 publications

(17 citation statements)

References 27 publications

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“…This is consistent with the experimental observation [12] that the charge is larger on the particles close to the wall surface when they flow through a metal cylinder. The charge and charge-to-mass ratio can reach equilibrium after a period of mixing or blend as shown experimentally [39,40]. In addition, the smaller particles tend to have a faster charging process and a higher charge level (net charge or charge-to-mass ratio), as predicted by this current study.…”

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confidence: 77%

Numerical analysis of contact electrification of non-spherical particles in a rotating drum

Chen

Adams

2015

Powder Technology

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Contact electrification is generally referred to as the charge transfer process between particles during collisions. The transferred charge can be accumulated on the surface of the particles especially for insulating materials with irregular shapes, which can lead to a non-uniform charge distribution and eventually affects the charge accumulation process. In this study, in order to investigate the influence of the particle shape on contact electrification, a sphere-tree multi-sphere method and a contact electrification model are implemented into the discrete element method (DEM) to model the charging process of irregular particles in a rotating drum. Irregular particles with various Sauter mean diameters but the same maximum diameter and equivalent volume diameters are considered. The charge distribution and accumulation on the particles are investigated. It is found that the charge transfer originates from the contact between the particle and the drum due to the contact potential difference and ζ Presently with Department of Materials Science and Metallurgy, University of Cambridge, Cambridge, CB3 0FS, UK * Corresponding author: Tel: 01483683506. Email: c.y.wu@surrey.ac.uk 2 initially takes place primarily at the region near the wall of the drum. The charge eventually propagates to the entire granular bed. The charge of the particles increases exponentially to an equilibrium value. For particles with the same maximum diameter, a larger charging coefficient is obtained for the particles with smaller Sauter mean diameters and sphericities, which lead to a faster charge accumulation, while for particles with the same equivalent volume diameter and fill ratio, similar charging coefficients are observed. A non-uniform intra-particle charge distribution is induced on each individual multi-sphere particle.

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confidence: 77%

Numerical analysis of contact electrification of non-spherical particles in a rotating drum

Chen

Adams

2015

Powder Technology

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“…Statistical DOE studies have been carried out by Karner et.al 104,105 to investigate the influence and interactions of particle size, container size and concentration of fines. Detailed studies of a range of particle sizes, suggested that the magnitude of the charge increases continuously with decrease in particle size.…”

Section: Process and Formulation Parametersmentioning

confidence: 99%

Triboelectrification: A review of experimental and mechanistic modeling approaches with a special focus on pharmaceutical powders

Naik

Mukherjee

Chaudhuri

2016

International Journal of Pharmaceutics

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“…Segregation and agglomeration are two main problems frequently faced in powder-mixing processes, resulting in drug content homogeneity problems (Cartilier and Moës, 1989). Recently, there has been increased attention towards the tribocharging phenomenon during powder blending processes (Karner and Urbanetz, 2012;Zhu et al, 2007). The control of powder charge is important to maximise mixing efficiency (Engers et al, 2007).…”

Section: Blending and Drug Content Homogeneitymentioning

confidence: 99%

A review of factors affecting electrostatic charging of pharmaceuticals and adhesive mixtures for inhalation

Kaialy

2016

International Journal of Pharmaceutics

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Pharmaceutical powders are typically insulators consisting of relatively small particles and thus they usually exhibit significant electrostatic charging behaviours. In the inhalation field, the measurement of electrostatic charge is an imperative stage during pharmaceutical formulation development. The electrostatic charge is affected by the interplay of many factors. This article reviews the factors affecting the electrostatic charging of pharmaceutical powders with a focus on dry powder inhalations. The influences of particle resistivity, size distribution, shape distribution, surface roughness, polymorphic form and hygroscopicity, as well as the effects of moisture uptake, environmental conditions, pharmaceutical processing (i.e., milling, sieving, spray drying and blending), and storage on the electrostatic charge behaviours of pharmaceuticals, with focus on inhalation powders, were reviewed. The influence of electrostatic charge on the performance of dry powder inhaler formulations in terms of drug content homogeneity, the passage of drug through the inhaler device, drug-carrier adhesion/detachment, and drug deposition on the respiratory airways were discussed. The understanding gained is crucial to improving the safety, quality, and efficiency of the pharmaceutical inhalation products.

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Arising of electrostatic charge in the mixing process and its influencing factors

Cited by 24 publications

References 27 publications

Numerical analysis of contact electrification of non-spherical particles in a rotating drum

Numerical analysis of contact electrification of non-spherical particles in a rotating drum

Triboelectrification: A review of experimental and mechanistic modeling approaches with a special focus on pharmaceutical powders

A review of factors affecting electrostatic charging of pharmaceuticals and adhesive mixtures for inhalation

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