Arieianal, a Prenylated Benzoic Acid from Piper arieianum

Abstract

A new prenylated benzoic acid, arieianal [3,4-dihydroxy-5-(E,E, E-11'-formyl-3',7',15'-trimethylhexadeca-2',6',10', 14'-tetraenyl)benzoic acid, 1], has been isolated from the leaves of Piper arieianum and assigned this structure on the basis of its spectral data.

The anti-inflammatory activity of dillapiole and some semisynthetic analogues

“…Some of these species are employed in popular medicine for the treatment of several different diseases (Duke, 1985;Parmar et al, 1997). Chemical investigations carried out on the essential oils of this genera of plants has uncovered the existence of monoterpenes, sesquiterpenes (Sengupta & Ray, 1987;Green et al, 1999) and phenylpropanoids, among other substances (Maxwell & Rampersad, 1989;Moreira et al, 2001). The chemical isolation and characterization of phenylpropanoids revealed a class of chemical compounds represented especially by dillapiole (1) and safrole (2) (Figure 1; Diaz et al, 1986;Bernard et al, 1995;Fazolin et al, 2005).…”

Isolation, Synthesis, and Evolutionary Ecology of Piper Amides

“…The bioassay-guided fractionation methods utilized by Wiemer and colleagues (Howard et al 1988, Capron and Wiemer 1996, Green et al 1999 have resulted in the isolation of ecologically important compounds from Piper (and other genera). This research focuses on compounds that are deterrent to leafcutting ants (Acromyrmex spp.…”

Crystal Structure of 3,4-Dihydroxy-5-Geranyl-Benzoic Acid

“…[13][14][15] In particular the HMBC and HSQC experiments were key in the elucidation of the structure ( Table 2). The structure of compound 5 was confirmed by x-ray diffraction analysis of a suitable single crystal (Fig.…”