Are Androgens Valuable in Management of Diabetes?

Abstract

The Influence of androgens on diabetes mellitus is a subject of extensive discussion. Testosterone effect in clinical trials commonly is evaluated in patients with diabetes type 2. In addition, the studies conducted on experimental models of diabetes (alloxan-and streptozotocininduced diabetes) also showed positive effects of androgen. Considering that experimental diabetes is more in line with diabetes type 1, it can be assumed that male sex hormone positively effects both types of diabetes. However, its influence may be realized by different pathways. Therefore, research of the opportunity of treatment of the various forms of diabetes with androgens, represents the active scientific and practical feature, which is waiting for the final verdict.