Architectured helically coiled scaffolds from elastomeric poly(butylene succinate) (PBS) copolyester via wet electrospinning

Sonseca, Águeda; Sahay, Rahul; Stępień, Karolina; Bukała, Julia; Wcislek, Aleksandra; McClain, Andrew; Sobolewski, Peter; Sui, Xiaomeng; Puskás, Judit E.; Kohn, Joachim; Wagner, H. Daniel; Fray, Mirosława El

doi:10.1016/j.msec.2019.110505

Cited by 34 publications

(34 citation statements)

References 53 publications

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“…The ideal polymers for this application are biodegradable, with structural stability and thermoplastic elastomers, with elastic modulus (E) in the range 0.1-100 MPa, these must be Página 7 | 26 biomimetic depending on the cardiac tissue to be replaced, which enable them to maintain their integrity to endure cyclic deformation and to transfer mechanical stress similar to cardiac muscle and blood vessels, while it allows cell growth [33]. Helically coiled scaffolds (HCS) can mimic the morphology and behavior of the heart muscle perimysium composed of microscale coiled fibers.…”

Section: Cardiac or Soft Tissue Engineeringmentioning

confidence: 99%

“…Helically coiled scaffolds (HCS) can mimic the morphology and behavior of the heart muscle perimysium composed of microscale coiled fibers. These scaffolds can mimic the morphology of the heart muscle, provide superior adhesion, proliferation and deep cell infiltration due to their high porosity (Table 1) [33]- [36]. Sonseca et.…”

Section: Cardiac or Soft Tissue Engineeringmentioning

confidence: 99%

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Wet Electrospinning and its Applications: A Review

Suaza

Henao

2022

TecnoL.

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In wet electrospinning, a natural or synthetic polymer solution is deposited on a non-solvent liquid coagulant used as collector. This technique can create 3D nanofiber scaffolds with better properties (e.g., porosity and high surface area) than those of traditional 2D scaffolds produced by standard electrospinning. Thanks to these characteristics, wet electrospinning can be employed in a wide range of tissue engineering and industrial applications. This review aims to broaden the panorama of this technique, its possible fields of action, and its range of common materials. Moreover, we also discuss its future trends. In this study, we review papers on this method published between 2017 and 2021 to establish the state of the art of wet electrospinning and its most important applications in cardiac, cartilage, hepatic, wound dressing, skin, neural, bone, and skeletal muscle tissue engineering. Additionally, we examine its industrial applications in water purification, air filters, energy, biomedical sensors, and textiles. The main results of this review indicate that 3D scaffolds for tissue engineering applications are biocompatible; mimic the extracellular matrix (ECM); allow stem cell viability and differentiation; and have high porosity, which provides greater cell infiltration compared to 2D scaffolds. Finally, we found that, in industrial applications of wet electrospinning: (1) additives improve the performance of pure polymers; (2) the concentration of the solution influences porosity and fiber packing; (3) flow rate, voltage, and distance modify fiber morphology; (4) the surface tension of the non-solvent coagulant on which the fibers are deposited has an effect on their porosity, compaction, and mechanical properties; and (5) deposition time defines scaffold thickness.

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Section: Cardiac or Soft Tissue Engineeringmentioning

confidence: 99%

Section: Cardiac or Soft Tissue Engineeringmentioning

confidence: 99%

Wet Electrospinning and its Applications: A Review

Suaza

Henao

2022

TecnoL.

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“…On the other hand, and in addition to the two standard configurations mentioned above, several modifications have been studied. These modifications have been done according to specific needs; for example, horizontal dry electrospinning (Figure 2b) is used to obtain membranes based on hydrolyzed collagen and polyvinyl alcohol with potential use for wound protection [9], and vertical wet spinning (Figure 2c) is used to synthesize membranes from polyvinyl alcohol and poly(ethyleneimine), to remove heavy metals from wastewater [10]. In these examples, the collector can be either immersed in a liquid, or dry, (Figure 2d).…”

Section: Electrohydrodynamic Atomization (Ehda)mentioning

confidence: 99%

“…As the jet spreads through the air, the solvent in the solution evaporates, forming a polymeric micro or nanofiber. Finally, the fibers are deposited in the collector in the form of a nonwoven micro/nanofiber membrane [6][7][8][9][10][11].…”

Section: Electrohydrodynamic Atomization (Ehda)mentioning

confidence: 99%

Starch Biodegradable Films Produced by Electrospraying

Sánchez¹,

Vázquez²,

García-Hernández³

et al. 2022

Starch - Evolution and Recent Advances

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The use of particles obtained from biopolymers is of interest in fields such as bioengineering and nanotechnology, with applications in drug encapsulation, tissue engineering, and edible biofilms. A method used to obtain these particles is electrohydrodynamic atomization (EHDA), which can generate different structures depending on the process conditions and raw materials used, opening a wide range of research in the biopolymers field, where starch is considered an excellent material to produce edible and biodegradable films. This chapter is a compilation and analysis of the newest studies of this technique, using starch with or without modifications to prepare films or membranes and their potential applications. A systematic literature review, focused on starch, and EHDA was carried out, finding 158 articles that match these criteria. From these results, a search inside them, using the words edible and biodegradable was conducted, showing 93 articles with these key words. The information was analyzed observing the preference to use corn, potato, rice, and cassava starches, obtaining mainly scaffolds and fibers and, in much less proportion, films or capsules. This review shows a window of opportunity for the study of starchy materials by EHDA to produce films, coatings, and capsules at micro or nano levels.

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“…The lipase-catalyzed polycondensation reactions under solvent-less conditions have been carried out also for synthesis of polyesters from adipic acid and sebacic acid with different diols [12,[40][41][42][43] yielding different molar masses from 10 3 -to 10 4 g/mol. Aliphatic building blocks with unsaturated units can also be converted without crosslinking [25,[44][45][46][47][48]. Aliphatic-aromatic polyesters were prepared enzymatically as well [49].…”

Section: Introductionmentioning

confidence: 99%

Enzymatic Synthesis of Poly(alkylene succinate)s: Influence of Reaction Conditions

et al. 2021

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Application of lipases (preferentially Candida antarctica Lipase B, CALB) for melt polycondensation of aliphatic polyesters by transesterification of activated dicarboxylic acids with diols allows to displace toxic metal and metal oxide catalysts. Immobilization of the enzyme enhances the activity and the temperature range of use. The possibility to use enzyme-catalyzed polycondensation in melt is studied and compared to results of polycondensations in solution. The experiments show that CALB successfully catalyzes polycondensation of both, divinyladipate and dimethylsuccinate, respectively, with 1,4-butanediol. NMR spectroscopy, relative molar masses obtained by size exclusion chromatography, MALDI-TOF MS and wide-angle X-ray scattering are employed to compare the influence of synthesis conditions for poly(butylene adipate) (PBA) and poly(butylene succinate) (PBS). It is shown that the enzymatic activity of immobilized CALB deviates and influences the molar mass. CALB-catalyzed polycondensation of PBA in solution for 24 h at 70 °C achieves molar masses of up to Mw~60,000 g/mol, higher than reported previously and comparable to conventional PBA, while melt polycondensation resulted in a moderate decrease of molar mass to Mw~31,000. Enzymatically catalyzed melt polycondensation of PBS yields Mw~23,400 g/mol vs. Mw~40,000 g/mol with titanium(IV)n-butoxide. Melt polycondensation with enzyme catalysis allows to reduce the reaction time from days to 3-4 h.

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Architectured helically coiled scaffolds from elastomeric poly(butylene succinate) (PBS) copolyester via wet electrospinning

Cited by 34 publications

References 53 publications

Wet Electrospinning and its Applications: A Review

Wet Electrospinning and its Applications: A Review

Starch Biodegradable Films Produced by Electrospraying

Enzymatic Synthesis of Poly(alkylene succinate)s: Influence of Reaction Conditions

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