2008
DOI: 10.1007/978-1-4020-8649-6_8
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Applications of Nanotechnology in the Biomedical Sciences: Small Materials, Big Impacts, and Unknown Consequences

Abstract: Nanotechnology is at the forefront of a revolution in the biomedical sciences. It has the potential to give both researchers and doctors' abilities they would never have previously dreamt of, including everything from the capability to deliver engineered drugs to specific target tissues to filtering even the smallest harmful particles out of our water supply. With such increased power, however, also comes increased responsibility. Nanotechnologies have as much potential to do harm as they do good. For instance… Show more

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Cited by 8 publications
(7 citation statements)
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“…Telomeres are the names given to these ends [10], and they prevent chromosomes from fusing and causing abnormalities and protecting the chromosome ends from being nibbled away by cell enzymes [7,10,11]. Chromosomes are extremely valuable and must last a lifetime [12]. They replicate themselves with each cell division, but this also means that any damage sustained during the division process is passed on to the new cells [13].…”
Section: Introductionmentioning
confidence: 99%
“…Telomeres are the names given to these ends [10], and they prevent chromosomes from fusing and causing abnormalities and protecting the chromosome ends from being nibbled away by cell enzymes [7,10,11]. Chromosomes are extremely valuable and must last a lifetime [12]. They replicate themselves with each cell division, but this also means that any damage sustained during the division process is passed on to the new cells [13].…”
Section: Introductionmentioning
confidence: 99%
“…4 The recent advances in nanotechnology have provided a modicum of hope to cope with the fears caused by looming bacterial outbreaks. 5 Materials at the nanoscale exhibit properties that are not seen or believed to exist in the bulk scale of the same materials. 6 Nanotechnology and nanomaterials have been in existence for long time, for example silver and silver nanoparticles were some of the first antimicrobial materials used extensively in the ancient world.…”
Section: Introductionmentioning
confidence: 99%
“…Although the silver ions released from silver nanoparticles are undoubtedly toxic, there is still no conclusive evidence as to whether metallic silver nanoparticles themselves have particle-specific toxicity. Metallic silver is easily oxidized in acidic liquid solutions exposed to air to generate toxic silver ions; in fact, toxicity depends on the concentration of silver ions released under aerobic conditions (Whitman et al 2008). As shown in the studies, even a low dose of the silver nanoparticles have severe effects on the human macrophages (Haase et al 2011); they can cause changes in cellular DNA due to the formation of free radicals.…”
Section: R a F Tmentioning
confidence: 99%