Applications of carbon-based conductive nanomaterials in biosensors

Eivazzadeh‐Keihan, Reza; Noruzi, Ehsan Bahojb; Chidar, Elham; Jafari, Mahdokht; Davoodi, Farahnaz; Kashtiaray, Amir; Gorab, Mostafa Ghafori; Hashemi, Seyed Masoud; Javanshir, Shahrzad; Cohan, Reza Ahangari; Maleki, Ali; Mahdavi, Mohammad

doi:10.1016/j.cej.2022.136183

Cited by 162 publications

(86 citation statements)

References 200 publications

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“…These listed features acquired by this electrochemical method qualified it for mass production and commercialization. Nevertheless, the weakness of selectivity represented by the high interferences and cross-reactivity with other electroactive substances is considered a huge disadvantage and drawback [ 31 ]. Recently, an amperometric biosensor was developed by Yaping Dong et.…”

Section: Electrochemical-based Biosensorsmentioning

confidence: 99%

Advances in Electrochemical Nano-Biosensors for Biomedical and Environmental Applications: From Current Work to Future Perspectives

Hassan

2022

Sensors

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Modern life quality is strongly supported by the advances made in biosensors, which has been attributed to their crucial and viable contribution in point-of-care (POC) technology developments. POC devices are exploited for the fast tracing of disease progression, rapid analysis of water, and food quality assessment. Blood glucose meters, home pregnancy strips, and COVID-19 rapid tests all represent common examples of successful biosensors. Biosensors can provide great specificity due to the incorporation of selective bio-recognition elements and portability at significantly reduced costs. Electrochemical biosensor platforms are one of the most advantageous of these platforms because they offer many merits, such as being cheap, selective, specific, rapid, and portable. Furthermore, they can be incorporated into smartphones and various analytical approaches in order to increase their sensitivity and many other properties. As a very broad and interdisciplinary area of research and development, biosensors include all disciplines and backgrounds from materials science, chemistry, physics, medicine, microbiology/biology, and engineering. Accordingly, in this state-of-the-art article, historical background alongside the long journey of biosensing construction and development, starting from the Clark oxygen electrode until reaching highly advanced wearable stretchable biosensing devices, are discussed. Consequently, selected examples among the miscellaneous applications of nanobiosensors (such as microbial detection, cancer diagnosis, toxicity analysis, food quality-control assurance, point of care, and health prognosis) are described. Eventually, future perspectives for intelligent biosensor commercialization and exploitation in real-life that is going to be supported by machine learning and artificial intelligence (AI) are stated.

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Section: Electrochemical-based Biosensorsmentioning

confidence: 99%

Advances in Electrochemical Nano-Biosensors for Biomedical and Environmental Applications: From Current Work to Future Perspectives

Hassan

2022

Sensors

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“…These materials render mechanical constancy, a great surface-to-volume ratio, low cost, electrocatalytic characteristics etc. [ 56 , 57 , 58 , 59 , 60 ]. Specifically, Jamei et al fabricated an ultra-sensitive aptasensor based on polymer quantum dots and a C60/MWCNT polyethyleneimine (PEI) nanocomposite modified on the SPCE electrode surface to analyze TB ( Figure 3 ).…”

Section: Electrochemical Biosensorsmentioning

confidence: 99%

Recent Progresses in Development of Biosensors for Thrombin Detection

et al. 2022

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Thrombin is a serine protease with an essential role in homeostasis and blood coagulation. During vascular injuries, thrombin is generated from prothrombin, a plasma protein, to polymerize fibrinogen molecules into fibrin filaments. Moreover, thrombin is a potent stimulant for platelet activation, which causes blood clots to prevent bleeding. The rapid and sensitive detection of thrombin is important in biological analysis and clinical diagnosis. Hence, various biosensors for thrombin measurement have been developed. Biosensors are devices that produce a quantifiable signal from biological interactions in proportion to the concentration of a target analyte. An aptasensor is a biosensor in which a DNA or RNA aptamer has been used as a biological recognition element and can identify target molecules with a high degree of sensitivity and affinity. Designed biosensors could provide effective methods for the highly selective and specific detection of thrombin. This review has attempted to provide an update of the various biosensors proposed in the literature, which have been designed for thrombin detection. According to their various transducers, the constructions and compositions, the performance, benefits, and restrictions of each are summarized and compared.

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“…For instance, Zhe et al fabricated a self-supporting binder-free electrode using carbon cloth for the detection of nitrite, resulting in a LOD of 0.04 µM [ 34 ]. In addition, a carbon nanotube (CNT) is also a promising substrate for the development of superminiaturized chemical and biological sensors due to its high sensitivity to electronic properties and unparalleled large unit surface [ 35 , 36 , 37 , 38 , 39 ]. Geng et al developed an efficient SSE using Ni/MoC encapsulated by nitrogen-doped carbon nanotube arrays on carbon cloth for overall water splitting [ 29 ].…”

Section: Introductionmentioning

confidence: 99%

A High-Performance Self-Supporting Electrochemical Biosensor to Detect Aflatoxin B1

et al. 2022

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High-performance electrochemical biosensors for the rapid detection of aflatoxin B1 (AFB1) are urgently required in the food industry. Herein, a multi-scaled electrochemical biosensor was fabricated by assembling carboxylated polystyrene nanospheres, an aptamer and horseradish peroxidase into a free-standing carbon nanofiber/carbon felt support. The resulting electrochemical biosensor possessed an exceptional performance, owing to the unique structures as well as the synergistic effects of the components. The 3D porous carbon nanofiber/carbon felt support served as an ideal substrate, owing to the excellent conductivity and facile diffusion of the reactants. The integration of carboxylated polystyrene nanospheres with horseradish peroxidase was employed as a signal amplification probe to enhance the electrochemical responses via catalyzing the decomposition of hydrogen peroxide. With the aid of the aptamer, the prepared sensors could quantitatively detect AFB1 in wine and soy sauce samples via differential pulse voltammetry. The recovery rates of AFB1 in the samples were between 87.53% and 106.71%. The limit of detection of the biosensors was 0.016 pg mL−1. The electrochemical biosensors also had excellent sensitivity, reproducibility, specificity and stability. The synthetic strategy reported in this work could pave a new route to fabricate high-performance electrochemical biosensors for the detection of mycotoxins.

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Applications of carbon-based conductive nanomaterials in biosensors

Cited by 162 publications

References 200 publications

Advances in Electrochemical Nano-Biosensors for Biomedical and Environmental Applications: From Current Work to Future Perspectives

Advances in Electrochemical Nano-Biosensors for Biomedical and Environmental Applications: From Current Work to Future Perspectives

Recent Progresses in Development of Biosensors for Thrombin Detection

A High-Performance Self-Supporting Electrochemical Biosensor to Detect Aflatoxin B1

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